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Beca de investigación. Búsqueda de empresas del campo de diagnóstico avanzado o desarrollo de pruebas de diagnóstico complementarias para enfermedades complejas

Resumen

Tipo:
Búsqueda de socios
Referencia:
RDIT20170529007
Publicado:
23/06/2017
Caducidad:
23/06/2018
Resumen:
Un grupo de investigación italiano ha desarrollado un tratamiento personalizado con glucocorticoides para diagnosticar el síndrome nefrótico, un método basado en análisis genético y epigenético para una terapia personalizada. El grupo de investigación busca empresas del sector de diagnóstico avanzado o desarrollo de pruebas de diagnóstico complementarias para enfermedades complejas. Gracias a la subvención regional de una beca de un año, podrán desarrollarse conjuntamente los resultados de investigación. La fecha límite de la convocatoria es el 30 de agosto de 2017 y el plazo para presentar expresiones de interés finaliza el 15 de julio.

Details

Tittle:
Research grant - Looking for companies active in the field of advanced diagnostics or in the development of companion diagnostic tests for complex diseases
Summary:
An Italian research group has developed personalized glucocorticoid therapy for nephrotic syndrom diagnostic (a method based on genetic and epigenetic analysis for a personalized therapy). They are looking for companies active in the field of advanced diagnostics or involved in the development of companion diagnostic tests for complex diseases. A regional grant can support the co-development of the research results by paying the costs of one year research fellowship.
Description:
An Italian research group has developed personalized glucocorticoid therapy for nephrotic syndrom diagnostic.
The main objective of the research is the development of an accurate and fast diagnostic test based on the study of the genetic and epigenetic mechanisms that lead to clinical response variability to glucocorticoids. The tool will allow to distinguish the different subgroups of patients (resistant, dependent and responsive) affected by nephrotic syndrome in order to personalize the glucocorticoid treatment. The tool will be developed considering the methylation status of two candidate genes, previously associated to glucocorticoid´s treatment response in leukemic patients, in combination with genome-wide analysis of other potential relevant sites and with miRNA analysis. The diagnostic kit will have clinical usefulness in order to develop an effective and personalized glucocorticoids therapy for patients, improving the treatment outcomes.

They are preparing a project proposal that can fund (thanks to a regional programme) one year fellowship grant.

They are looking for a company active in the field of advanced diagnostics or involved in the development of companion diagnostic tests for complex diseases that are interested in the co-development of the technology.

The company role will be to collaborate with the research group and the dedicated fellow in order to achieve a proof-of-concept potentially ready to be used by the company.


Deadline of the call: 30/08/2017
Deadline for EoIs: 15/07/2017
Advantages and Innovations:
The technology will allow the improvement of the therapy for nephrotic syndrome with advantages to the patients and the health system, leading to the development of personalized medicine strategies for this complex pathology. Moreover, the use of the diagnostic kit could be extended to other pathologies, such as rheumatoid arthritis and chronic inflammatory bowel disease, in order to identify genetic and epigenetic markers related to glucocorticoids treatment response. The reduction of treatment failures and the improvement of the quality of life of the patients will lead to a superior level of therapy for nephrotic syndrome, reducing costs related to problem of efficacy of the drugs and toxicity of the therapy.

Partner sought

Partner Sought:
Type: companies active in the field of advanced diagnostics or involved in the development of companion diagnostic tests for complex diseases. Role: co-development of the research results with the aim of being exploited by the company.
Type of Partnership Considered:
RDR

Client

Type and Size of Client:
University
Already Engaged in Trans-National Cooperation:
No

Dissemination

Programme-call

Call name:
Health
Deadline for Call:
30/08/2017