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Beca de investigación. Búsqueda de empresas en el sector de nuevos tratamientos para enfermedades neurodegenerativas

Resumen

Tipo:
Búsqueda de socios
Referencia:
RDIT20170526004
Publicado:
21/06/2017
Caducidad:
21/06/2018
Resumen:
Un grupo de investigación italiano ha desarrollado dos técnicas moleculares innovadoras (RT-QuIC y PMCA) para la detección temprana y definitiva de enfermedades neurodegenerativas. El grupo de investigación busca compañías farmacéuticas en el campo de nuevos tratamientos para enfermedades neurodegenerativas o empresas de outsourcing implicadas en el proceso de descubrimiento de fármacos para enfermedades neurológicas. Gracias a una subvención regional, podrán desarrollarse conjuntamente los resultados de investigación con una beca de un año. La fecha límite de la convocatoria es el 30 de agosto de 2017 y el plazo para presentar expresiones de interés finaliza el 15 de julio.

Details

Tittle:
Research grant - Looking for companies active in the field of new treatments for neurodegenerative disorders
Summary:
An Italian research group has developed two innovative molecular techniques (RT-QuIC and PMCA) for an early and definitive detection of neurodegenerative diseases. They are looking for pharmaceutical companies active in the field of new treatments for neurodegenerative disorders or outsourcing companies involved in the process of drug discovery for neurological diseases. A regional grant can support the co-development of the research results by paying the costs of one year research fellowship.
Description:
The Italian research group with longstanding expertise in international reseach projects has developed innovative tecniques that can be tested by potential partners.
RT-QuIC and PMCA are fast in vitro assay that can detect disease-specific biomarkers with high sensitivity and specificity thus enabling early and definitive diagnosis of neurodegenerative diseases. These two techniques enable the detection of minute infectious prion proteins (undetectable by current diagnostic techniques) in peripheral tissues (e.g. urine, blood, cerebrospinal fluid and olfactory mucosa) of patients in early stages of neurodegenerative diseases and can model the process of protein misfolding and aggregation in vitro.

They are preparing a project proposal that can fund (thanks to a regional programme) one year fellowship grant.

They are looking for a company active in the field of new treatments for neurodegenerative disorders interested in the co-development of the technology. The company role will be to collaborate with the research group and the dedicated fellow in order to achieve the proof-of-concept (potentially ready to be used by the company).

Deadline of the call: 30/08/2017
Deadline for EoIs: 15/07/2017
Advantages and Innovations:
The two approaches are fast and can achieve an early and definitive diagnosis of dementia without the need of costly and invasive procedures. It is possible to obtain patients stratifications´ useful for diagnostic and therapeutic purposes and assess the efficacy of different and innovative therapeutic compounds or drugs to interfere with the individual misfolding process. Moreover the techniques will allow the specific monitor of disease progression by analyzing the variation of disease-specific biomarkers, providing the patients with the most efficient compounds able to interfere with the molecular events and not only with the symptoms of the diseases.

Partner sought

Partner Sought:
Type: pharmaceutical companies active in the field of new treatments for neurodegenerative disorders or outsourcing companies involved in the process of drug discovery for neurological diseases. Role: co-development of the research results.
Type of Partnership Considered:
RDR

Client

Type and Size of Client:
R-Y-D Institution
Already Engaged in Trans-National Cooperation:
No

Dissemination

Programme-call

Call name:
Health
Deadline for Call:
30/08/2017