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Convocatoria H2020 SC1-PM-16-2017: Búsqueda de socios para evaluar el impacto en la salud y socio-económico de ensayos in-silico

Resumen

Tipo:
Búsqueda de socios
Referencia:
RDFR20161202001
Publicado:
02/12/2016
Caducidad:
02/12/2017
Resumen:
Un consorcio liderado por una universidad francesa está preparando una propuesta para la convocatoria H2020 SC1-PM-16-2017 "Ensayos in-silico para desarrollar y evaluar productos biomédicos". El objetivo del proyecto es ofrecer un nuevo modelo fisiológico y digital en 3D de la perfusión hepática capaz de simular la inyección de un medicamento y su impacto en tejidos sanos y lesiones hepáticas. El equipo de investigación busca socios públicos y privados en los sectores de economía y salud pública para analizar el impacto económico del proyecto. La fecha límite de la convocatoria es el 14 de marzo de 2017 y el plazo para presentar expresiones de interés finaliza el 27 de enero de 2017.

Details

Tittle:
H2020 SC1-PM-16-2017 call: Partners sought for evaluation of health and socio-economic impacts of in-silico trials.
Summary:
A French-based consortium is preparing a proposal for the Horizon 2020 SC1-PM-16-2017 call: "In-silico trials for developing and assessing biomedical products". The project is to propose a novel 3D-digital and physiological model of the liver perfusion, capable of simulating the injection of a drug and its impact upon healthy tissues and hepatic lesions. The research team is looking for private or public partners in economics and public health to evaluate the project´s economic impacts.
Description:
The development of in-silico trials is an international scale challenge. The European Commission strongly promotes reduction of animal testing and human trials, as evidenced by several Horizon 2020 calls in Health Societal challenge.

A French university is building a consortium to propose in-silico trials based on a novel 3D-digital and physiological model of the liver perfusion to test the injection of drugs for the treatment of hepatic diseases. This will help medical doctors to plan protocols faster and better, as they will benefit from a computerized prediction of the effect of one or several drugs on a patient, before employing it practically.

The project requires a high multi-disciplinarity including:
- ICT : computer vision, medical image processing, digital geometry.
- Medicine: clinical practice, hepatology, hepatic surgery.
- Chemistry, Physiology: identification of optimal parameters for the in-silico trial, assessment of drug delivery and action
-Economics: Estimates of benefits for human health (and animal welfare), cost-effectiveness and cost-utility modeling.

The consortium is looking for public or private partners specialized in medico-economic studies with decision-making tools aimed at optimizing the use of 3D-model of the liver perfusion and in-silico trial model as well as evaluating the economic impacts in terms of health outcomes at a population level.

The project will be submitted on the H2020 Personalised Medicine programme SC1-PM-16-2017 call which has a deadline 14 March 2017, 17h.
The deadline for expression of interest is January 27th.

Advantages and Innovations:
The main goal is to develop a 3D-model for relevant clinical trials that can be personalized to each patient.

The proposed project is expected to provide a low-cost and reusable in-silico model that could act as a supporting tool design to evaluate the drug efficiency.

This would allow a reduction of animal testing and human clinical trials.
Stage of Development:
Project in negotiations - urgent
IPR Status:
Secret Know-how

Partner sought

Partner Sought:
The consortium is looking for public or private partners specialized in medico-economic studies with decision-making tools aimed at optimizing the use of 3D-model of the liver perfusion and in-silico trial model as well as evaluating the economic impacts in terms of health outcomes at a population level. Type of partners: research and academic institutions , private companies Specific area: medico-economic evaluation - Strategic guidance and recommendations for cost-effectiveness studies, and for quantification of benefits for human health (and animal welfare) - Development of budget impact models.
Type of Partnership Considered:
RDR

Client

Type and Size of Client:
University
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English
French

Dissemination

Programme-call

Anticipated Project Budget:
6 000 000 euros
Coordinator Required:
No
Deadline for Call:
14/03/2017
Project Duration:
0