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Convocatoria HDHL-INTIMIC: Búsqueda de socios clínicos para un estudio sobre el impacto de diferentes hábitos alimenticios europeos en la composición y función de la microbiota intestinal en una propuesta del cáncer colorrectal

Resumen

Tipo:
Búsqueda de socios
Referencia:
RDIT20170316001
Publicado:
24/03/2017
Caducidad:
24/03/2018
Resumen:
Una universidad italiana está desarrollando una propuesta dentro del esquema ERA.Net Cofund HDHL-INTIMIC (JPI HDHL), con fecha límite el 5 de abril de 2017. El objetivo es estudiar la composición de la microbiota intestinal en pacientes con cáncer colorrectal. En el proyecto se estudiarán importantes aspectos sobre las relaciones de causa y efecto entre la dieta, el micribioma intestinal y la salud humana. El objetivo global es crear una base de conocimiento sólida para desarrollar nuevas estrategias y productos que mejoren la salud y prevenir enfermedades crónicas mediante la modulación dependiente de la dieta del microbioma intestinal. La universidad busca socios clínicos en Europa, preferiblemente en Suecia, Holanda, Bélgica o Austria, con experiencia en cáncer colorrectal.

Details

Tittle:
Call HDHL-INTIMIC: Clinic sought for a study of the impact of different European dietary habits on the gut microbiota composition and function in colorectal cancer proposal
Summary:
An University from Central Italy is developing a proposal for the HDHL-INTIMIC, 2nd ERA-Net Cofund within JPI HDHL with deadline 5th of April 2017.
The proposal proposes a study of the gut microbiota composition in Colorectal cancer patients.
The applicant is looking for a clinical European partner (preferentially from Sweden, the Netherlands, Belgium or Austria), with expertise The partner should be a clinician expert in colon cancer oncology.
This search is active by 27 March.
Description:
Colorectal cancer (CRC) is the third most frequent tumor types worldwide, with highest incidence in developing countries. Diet components are the major source of mutagenic compounds that may cause both, initiation and tumor progression, being considerate the most important exogenous factor in the etiology of CRC. Diets can also influence the gut microbiota (the microbe population living in our intestine) composition. Since the Mediterranean diet is considered one of the most effective diet for the prevention/improvement of intestinal diseases the aim of the project is to evaluate if the CRC patients have a common (bacterial communities) gut microbiota despite having a different diets.

An Italian University with depth experience in the fields is planning to enrol CRC patients with different dietary habits (Mediterranean and continental). The requested partner should be a European clinician (University or Hospital), expert in colon cancer, involved in the enrolment of patients, in the collection of specimens and clinical data of the CRC patients and healthy controls.

The proposal will be submitted on the first joint transnational call of HDHL-INTIMIC "Interrelation of the Intestinal Microbiome, Diet and Health". It aims to support multinational, collaborative research projects that address important research questions regarding the cause-and-effect relationships between diet, the intestinal microbiome and human health. The overall aim of HDHL-INTIMIC is to build a solid knowledge base for the development of new strategies and products for health promotion and prevention of chronic diseases through diet-dependent modulation of the intestinal microbiome. The deadline to submit pre-proposal is the 5th of April.
The partner search deadline is 27th of March.
Advantages and Innovations:
The project aims to give a more accurate identification of gut bacterial groups which could have discriminatory properties in CRC spectrum balance. So, results can be very useful to understand if diet-related variations could modulate therapeutic interventions in CRC patients.
Stage of Development:
Proposal under development
Technical Specification or Expertise Sought:
The requested partner is a European clinician (University or hospital) , expert in colon cancer, that will be involved in the enrolment of CRC patients, in the collection of specimens ( serum and fecal samples) and clinical data ( metadata) of the CRC patients and healthy controls.
IPR Status:
Secret Know-how

Partner sought

Partner Sought:
The requested partner is a European clinician (University or Hospital), expert in colon cancer, that will be involved in the enrolment of CRC European patients, in the collection of specimens ( serum and fecal samples) and clinical data (metadata) of the CRC patients and healthy controls.
Type of Partnership Considered:
RDR

Client

Type and Size of Client:
University
Already Engaged in Trans-National Cooperation:
No
Languages Spoken:
English

Dissemination

Restrict dissemination to specific countries:
Austria
Belgium
France
Germany
Netherlands
Spain
Sweden

Programme-call

Coordinator Required:
No
Deadline for Call:
05/04/2017
Project Duration:
0