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H2020-SFS-15-2016-2017: Búsqueda de investigadores y granjas lecheras para participar en un proyecto de salud de vacas lecheras

Resumen

Tipo:
Búsqueda de socios
Referencia:
RDDE20160201001
Publicado:
04/02/2016
Caducidad:
04/02/2017
Resumen:
Un instituto de anatomía veterinaria de una universidad alemana busca investigadores especializados en salud animal, en particular en salud de vacas lecheras, con el fin de presentar una propuesta a la convocatoria H2020-SFS-15. El objetivo es analizar los vasos sanguíneos de vacas lecheras de alta producción y compararlos con los vasos sanguíneos de otros grupos de animales de granja para investigar sus malas condiciones de salud y baja tasa de fertilidad. Los socios buscados incluyen institutos de investigación y granjas con acceso a información sobre la salud de vacas lecheras. La fecha límite de la convocatoria es el 17 de febrero de 2016 y el plazo para presentar expresiones de interés finaliza el 10 de febrero.

Details

Tittle:
H2020-SFS-15-2016-2017: looking for researchers and dairy farmers for dairy cow health project
Summary:
The institute of veterinary anatomy of a German university is looking for research partners active in animal health, particularly dairy cow health for the call H2020-SFS-15. The project aims at examining the blood vessels of high-producing dairy cows and compare those with the blood vessels of other groups of farm animals in order to investigate their poor health conditions and low fertility. Partners should be research institutes or dairy farms with detailed access to dairy cow health data.
Description:
High-producing dairy cows often suffer from poor health and low fertility and this even at a young age. These health issues, which are also a sign of ageing, include ovarian, uterine and placental dysfunction, disorders of the mamma, hepatopathy and impaired wound healing. A reason for the disorders mentioned could be inadequate proliferation, reparation and regeneration of various tissues, particularly of blood vessels. This is also the case in aging organisms, since vascularization plays a fundamental role in the cyclic processes in ovary and uterus, during the development of the placenta, during the formation of the mamma as well as in wound healing.
The two mechanisms that mainly regulate vascularization are vasculogenesis and angiogenesis. Whereas angiogenesis is the formation of capillaries by sprouting of endothelial cells from pre-existing blood vessels, vasculogenesis is the de novo formation of primitive blood vessels by migration and differentiation of endothelial stem and progenitor cells in situ. According to the latest scientific findings, the vascular endothelial cells that are crucial in this process arise from stem cells that can be found in organs of the adult organisms, especially in the wall of blood vessels. The institute´s work group has been investigating models of angiogenesis and vasculogenesis in vitro, in vivo and in situ, respectively, for years.
There is a close connection between the ability of regeneration and the resources of stem cells. The work group has identified adult endothelial stem cells in the ovaries of dairy cows, on a morphological as well as immunohistochemical level.
The new project is based on the hypothesis that the availability of stem or progenitor cells plays a fundamental role in productivity and physical resilience in high-producing dairy cows. The assumption is that the resources of stem cells in high-producing dairy cows are used up sooner and their generally poor health is related to this fact and may even be comparable to early ageing.
It is their objective to prove that high-producing dairy cows suffer from an advanced senescence of vascular endothelial cells or a premature consumption of their stem cells, leading to inadequate vasculogenesis as well as angiogenesis and accelerated ageing.
As part of this project, the work group is planning to examine the blood vessels of high-producing dairy cows and compare those with the blood vessels of other groups of farm animals (dual purpose cows). See below for a list of key points comprising the work program:
a) Morphological and ultrastructural characterization of blood vessels
b) Identification, characterization and quantification of endothelial cells and their stem cells
c) Profiling of data on early detection and risk assessment of cow families with advanced senescence, as relevant for breeders

The partner should be a research institute or a dairy farm with extensive health monitoring tools for high-producing dairy cows. The consoritum will be coordinated by the German university issuing this partner request.

The deadline for EOIs is 10 February 2016. The deadline for the call is 17 February 2016. The project is expected to last 3 years.
Stage of Development:
Proposal under development

Partner sought

Partner Sought:
The partner should be a research institute or a dairy farm with extensive health monitoring tools for high-producing dairy cows. Specific area of activity of the partner: - high producing dairy cow, cattle, dual-purpose breed, animal welfare, sustainability, animal breeding, genetic, livestock systems, productivity of agricultural animals, breeding, terrestrial livestock for improved resilience and efficiency, intensive farming vs. organic farming Field of expertise/experience: - ageing, senescence, stem cells, high producing dairy cow, animal breeding, genetic, livestock systems, productivity of agricultural animals, breeding, terrestrial livestock for improved resilience and efficiency, intensive farming vs. organic farming Task to be performed by the partner sought: - Has access to data with respect to certain parameters: various age groups, environmental conditions, management, milking technology, size of operation, feeding, hygiene, animal husbandry, grazing area, cow barn - cow shed, access to outdoor areas, distress Has access to data: - Data collection on most frequent causes of selection, udder diseases
Type of Partnership Considered:
RDR

Client

Type and Size of Client:
University
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English
German

Dissemination

Programme-call

Evaluation Scheme:
Two-stage submission scheme
Anticipated Project Budget:
7 Mio EUR
Coordinator Required:
No
Deadline for Call:
17/02/2016
Project Duration:
0