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A Polish medical university is offering innovative enteral flexible films for production of gastro-resistant capsules under license agreement

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOPL20211020002
Publicado:
18/11/2021
Caducidad:
19/11/2022
Resumen:
A leading Polish medical university has developed an innovative enteral flexible film for production of gastro-resistant capsules. It is now looking for foreign licensees that are willing to obtain IP rights to this product together with the descriptions of the method of production in order to introduce it to the market.

Details

Tittle:
A Polish medical university is offering innovative enteral flexible films for production of gastro-resistant capsules under license agreement
Summary:
A leading Polish medical university has developed an innovative enteral flexible film for production of gastro-resistant capsules. It is now looking for foreign licensees that are willing to obtain IP rights to this product together with the descriptions of the method of production in order to introduce it to the market.
Description:
A leading Polish medical university has designed an innovative enteral flexible films for production of gastro-resistant capsules.
Modifying the release time of the active substance of the pharmaceutical is an important factor influencing the effectiveness and efficiency of the therapy. The use of gastro-resistant capsules allows protection of active substance against the action of gastric juice, release and absorption only in the intestines.

In addition, this form of drug administration protects the gastric mucosa from the irritating action of the active substance. Gastro-resistant capsules are coated with a substance from insoluble polymer with an acidic pH, and soluble at pH greater than 6 gastric juice environment. Unlike tablets, this technology does not work in case of capsules which are technologically difficult to coat. In response to the needs of the pharmaceutical market, the univesity proposes an innovative way of obtaining gelatinous mass, from which soft gelatine capsules can be made, that are characterized in gelatine casing being not easily insoluble in the gastric juice and which can release the contents when dissolved in the gastric juice after a prolonged period of time.

The technology of their production was disclosed in the patent and it is the subject of technological offer. This product is on a TRL-V level and is protected by a registered Polish and European patents.

The university is offering to sell license/IP rights for the new aqueous composition for making enteric films used in manufacturing of soft capsules characterized by delayed release of active substances and the descriptions of the method of making the gelatine film for the capsule preparation to a foreign partner.
Advantages and Innovations:
In evaluating innovativeness and competitive advantage, it must be noted that it has not been previously reported in scientific publications how to produce soft, gastro-resistant capsules. Attempts to modify the gelatine casing ensuring its stability in the acidic environment have been made, however, they have not been successful or ended with such a change in the elasticity of the gelatine film that it could not be applied in the manufacturing of soft capsules. The indicated improvement of physical and mechanical properties of the gelatine film combined with the easy way of manufacturing process makes the present solution useful and desirable for use in soft capsule manufacturing technology.
Stage of Development:
Available for demonstration
IPs:
Patents granted

Partner sought

Type and Role of Partner Sought:
Most suitable partners would be companies from Life Science sector with experience in carrying research and development works as well as in implementation of medicinal products on local and international markets.

Client

Type and Size of Client:
University
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English
Polish

Keywords

Technology Keywords:
06001015 Productos farmacéuticos / medicamentos