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Biogenesis on-demand for the production of carotenoids and phytonutrients

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOES20200922001
Publicado:
06/10/2020
Caducidad:
07/10/2021
Resumen:
Two Spanish research institutions have developed a biotechnological method for the biofortification in carotenoids and other phytonutrients of green tissues. The method is based on the controlled induction of chromoplasts. The mechanism could be applied to the development of novel functional foods or bio factories for a variety of industries. Industrial partners are being sought to collaborate through a patent licence agreement.

Details

Tittle:
Biogenesis on-demand for the production of carotenoids and phytonutrients
Summary:
Two Spanish research institutions have developed a biotechnological method for the biofortification in carotenoids and other phytonutrients of green tissues. The method is based on the controlled induction of chromoplasts. The mechanism could be applied to the development of novel functional foods or bio factories for a variety of industries.

Industrial partners are being sought to collaborate through a patent licence agreement.
Description:
Controlling chromoplast differentiation has been proposed as a very promising strategy to improve the nutritional and health benefits of crops and for other biotechnological efforts, due to its unique ability to accumulate large amounts of carotenoids (pro-vitamin A) and other antioxidants and dietary nutrients such as tocopherols (vitamin E).

The present work shows for the first time that the supply of a sufficiently large quantity of phytoene in chlorophyll-containing plastids (chloroplasts) leads to their artificial or synthetic transformation into carotenoid and tocopherol-accumulating plastids (chromoplasts) in green tissues.

The method proposes agroinfiltration or any alternative method such as the use of viral vectors for the supply of phytoene to the chloroplasts of plants or crops once their photosynthetic activity is dispensable (for example, just before harvest).
Advantages and Innovations:
- Technology applicable to the nutritional improvement (biofortification) of cell cultures, leafy vegetables, green fruits, crops for human consumption and forage crops.

- Better use of the potential of crops. The method would allow the creation of bio factory plants to obtain products of interest to the cosmetic, pharmaceutical and food industries, such as carotenoids and tocopherols (natural pigments, antioxidants and essential phytonutrients).

- Compatible with a localized use in the plant (for example, the leaves that are not commercialized as biofactories can be used and the fruits, seeds, tubers and roots can be left intact).

- Method free of chemical pollutants or substances harmful to the environment, such as nitrogenous fertilizers or antibiotics.
Stage of Development:
Prototype available for demonstration
IPs:
Patent(s) applied for but not yet granted
CommeR Statunts Regarding IPR Status:
European patent application

Partner sought

Type and Role of Partner Sought:
Industrial partner in the agricultural biotechnology sector interested in the development and commercialization of the technology under a license agreement are sought.
Licensing agreement: the partner would license the technology to carry out the final development and commercialization of the tool.
Research cooperation agreement: the partner and the Spanish Institutions could undertake a joint effort to further develop and optimize the method, addressing to specific needs of the sector.

Client

Type and Size of Client:
R&D Institution
Already Engaged in Trans-National Cooperation:
No
Languages Spoken:
English
Spanish

Keywords

Technology Keywords:
07001004 Gestión de cosechas