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Complemento alimenticio para aumentar la masa muscular y combatir la sarcopenia relacionada con la edad sin reducir el apetito


Oferta Tecnológica
Una universidad británica ha desarrollado un complemento alimenticio pendiente de patente para combatir la sarcopenia relacionada con la edad y la pérdida de masa y resistencia muscular sin reducir el apetito. El complemento contiene las cantidades óptimas de L-leucina y aminoácidos esenciales y, a diferencia de otros suplementos proteínicos, no reduce el apetito. Se buscan productores de complementos y otras organizaciones interesadas para establecer acuerdos de licencia exclusivos y no exclusivos.


Nutritional supplement for enhancing muscle mass and countering age-related sarcopenia without reducing appetite
A UK university has developed a patent pending nutritional supplement to address the problem of age related sarcopenia associated with loss of muscle mass and strength. The supplement contains optimal amounts of L-leucine and essential amino acids and does not reduce appetite like other protein supplements. The organisation is looking for non-exclusive and exclusive license arrangements with supplement producers or other interested organisations.
As age increases beyond 60, health needs can become more complex and costly. The health and economic benefits of maintaining healthy ageing and quality of life in this age group can be substantial and this fact has underpinned the research undertaken by this university.

Present in 13% of 60-70 year old people, and up to 50% of people aged 80 years and over, sarcopenia is defined by the European Working Group on Sarcopenia in Older People (EWGSOP) as the presence of low muscle mass, together with either low muscle strength or low physical performance. Sarcopenia is a consequence of normal ageing and does not require a disease to occur, although muscle mass loss can be accelerated by illness. To put this into perspective, after the age of 40 humans lose approximately 1% of their muscle mass per year and consequently their physical activity is decreased. This natural deterioration contrasts with the need to maintain muscle mass and physical function so fundamental to promoting health and independence with age. The impact of good muscle mass for the prevention of falls, fracture and disability is also relevant. Falls and consequent injuries are a major public health problem because of a need for hospitalisation, and subsequent increases in morbidity and mortality.

Nutritional interventions have shown promising results as a means to combat age-related sarcopenia. A number of recent studies suggest that older individuals not only need to increase the amount of protein through their diets but they need to increase the contribution of individual essential amino acids that need to be ingested through the diet. However, increasing dietary protein through food alone can present other issues as increased protein intake suppresses appetite. Suppressed appetite results in inadequate energy intake which may exacerbate rates of age-related anorexia and subsequently decrease the amount of energy received through food, therefore accelerating rates of sarcopenia. This essential amino acid (EAA) nutritional product enriched with L-leucine has been shown to effectively provide the additional high-quality protein required but without suppressing appetite.

This UK based university is looking for license agreements with food supplement producers or other interested parties.
Advantages and Innovations:
- Provides optimum amounts of essential high-quality amino acids with L-leucine
- Does not suppress appetite like traditional protein supplements
- Formulation is optimised for the 60 age group
- Acceptable tasting product that can be incorporated into a bar or gel
- Prototype gel and bar developed which delivered leucine and essential amino acids in a more compact and palatable way.
- Food branding work has been undertaken
- Pilot study results have been published in a peer-reviewed publication
- Full research study under way to further explore the impact of these prototypes on appetite, appetite hormones, palatability and satiety
Stage of Development:
Field tested/evaluated
Patent(s) applied for but not yet granted

Partner sought

Type and Role of Partner Sought:
Type of partner sought - SME or larger company

Specific area of activity of the partner - Nutritional supplements, age-related

Task to be performed by the partner sought - licensing of technology


Type and Size of Client:
Already Engaged in Trans-National Cooperation:
Languages Spoken:


Technology Keywords:
08001002 Aditivos / ingredientes alimentarios / alimentos funcionales
08001005 Tecnología de alimentos