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Desarrollo y fabricación de vectores lentivirales

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOES20170908002
Publicado:
27/09/2017
Caducidad:
27/09/2018
Resumen:
Una pyme española, CDMO especializada en vectores lentivirales, ofrece una tecnología de desarrollo y fabricación de vectores lentivirales mediante el uso de un nuevo tipo de biorreactores. La tecnología presenta una alta escalabilidad entre biorreactores de diferentes tamaños y permite trabajar con varios biorreactores en paralelo. La empresa está especializada en fabricar vectores lectivirales de grado GMP, para investigación y toxicología preclínica. Se buscan compañías biotecnológicas o farmacéuticas con una línea de terapia genética que precisen desarrollar, producir o utilizar vectores lentivirales.

Details

Tittle:
Development and Manufacture of lentiviral vectors
Summary:
This Spanish SME is a lentiviral specialized CDMO offering personalized solutions based on the review of customer´s requirements and lentivirus vector design and cloning.
The company is specialized in the manufacture of research, preclinical toxicology and GMP-grade lentiviral vectors.

The company is looking to collaborate with Biotech/Pharma or biotechnology dedicated companies with a genetic therapy pipeline, with the need of developing, producing or using lentivirus vectors.
Description:
The company proposes herein a technology for the development and manufacture of Lentiviral vectors by using a new type of bioreactors in comparison with the classical static bioreactors.

The company´s bioreactor innovative technology allows obtaining relevant titter results comparing to other classical manufacturing technologies. Moreover, importantly, the company is developing both Upstream (USP) and Downstream (DSP) processes for a given batch.

Additionally, this innovation presents a greater scalability between different size bioreactors and allows working with several bioreactors in parallel.

The experience of more than two thousand lentiviral batches manufactured by the company made possible implementing this innovations within it´s manufacturing platform.

The company develops and manufactures lentiviral vectors from very early stages to the manufacture for preclinical toxicology or for advanced phases requiring GMP manufacture.
Advantages and Innovations:
Comparing to other companies developing and manufacturing lentiviral vectors, this profile offers the following advantages:
- Sealed as Excellence Centre by European Union.
- Own Lentivirus-based technology
- More than 2.000 lentiviral batches manufactured.
- iCELLis-nano bioreactor technology: Compatible equipment at R-Y-D and GMP suites.
- USP+DSP (Upstream and Downstream Process Development
- Improved transient transfection method.
- Increased final yield compared with regular protocols.
- Capacities, capabilities and infrastructure to increase current capacity.
Stage of Development:
Already on the market
IPs:
Secret Know-how
CommeR Statunts Regarding IPR Status:
Technology secrecy is assured by confidentiality agreements with colaborating companies.

Partner sought

Type and Role of Partner Sought:
The company is looking to collaborate with Biotech/Pharma or biotechnology dedicated companies with a genetic therapy pipeline, and with the need of developing, producing or using lentivirus vectors with specific characteristics.

The company offers itself to develope and produce these lentiviral vectors.

Client

Type and Size of Client:
Industry SME 11-49
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English
Spanish

Keywords

Technology Keywords:
06002002 Biología celular y molecular
06002001 Bioquímica / biofísica
06002005 Ingeniería genética
06001013 Tecnología médica / ingeniería biomédica