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Dietary supplements to protect from the harmful effects of environmental micropollutants

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOIT20210419001
Publicado:
22/04/2021
Caducidad:
23/04/2022
Resumen:
An Italian research group is prototyping an innovative dietary supplement, based on a new formulation that could contribute to disease prevention in populations exposed to concentrations of environmental micropollutants higher than the basal levels. The researchers are looking for financial, research cooperation or technical cooperation agreements in order to advance in the development of technology.

Details

Tittle:
Dietary Supplements to protect from the harmful effects of environmental micropollutants
Summary:
An Italian research group is prototyping an innovative dietary supplement, based on a new formulation that could contribute to disease prevention in populations exposed to concentrations of environmental micropollutants higher than the basal levels. The researchers are looking for financial, research cooperation or technical cooperation agreements in order to advance in the development of technology.
Description:
An Italian research group has developed an innovative dietary supplement to protect from the harmful effects of environmental micropollutants.
Environmental contamination is a prominent topic. Where the exposure to contaminants such as heavy metals (HMs) or polycyclic aromatic hydrocarbons (PAHs) is greater, the incidence of chronic degenerative diseases, such as oncologic, is increased. Scientific evidence reports that some phytochemicals are able to interact with HMs and PAHs by interfering with their cellular metabolism, inhibiting their cytotoxic mechanisms or helping to reduce tissue concentrations. In this context, the italian research group developed the idea of a formulation of phytochemicals to employ as bioactive ingredients in the production of a supplement that can contribute to the prevention of chronic-degenerative diseases linked to the exposure to HMs and PAHs in populations residing in areas affected by the environmental pollution problem. The same formulation is thought to be beneficial for the general population. Based on a rigorous literature screening and in vitro experimental data, a limited number of compounds have been selected, whose combination will allow the design of an optimal nutraceutical formulation based on the chemical-physical and biological characteristics of the selected molecules. The use of phytochemicals at non-pharmacological concentrations can help reducing the bioaccumulation and toxicity of organic and inorganic micropollutants, bringing beneficial effects to health.

The Italian researchers are interested in:
- Financial agreement: they are looking for a financial partner interested in investing on this project in order to advance in the development of the technology;
- Research Cooperation Agreement with another entity (research institutes or companies) to work together on this innovative research and on the development of new solutions
- Technical cooperation agreement: they wish to share with the partner(s) skills, technical and financial resources to implement the present technology and obtain a validated prototype to be tested in human subjects.

Advantages and Innovations:
The formulation is the result of experimental evidence and scientific literature data processed with a bioinformatic approach and data mining. In addition, the prototype will take into account the history of use in the nutritional field of the selected compounds, their safety profile and the availability of supply. There is scientific evidence that reports the potential role of compounds and / or extracts against different micropollutants. In addition, from an initial analysis emerged the absence on the nutraceutical market of products with similar application purposes.
Stage of Development:
Under development/lab tested
IPs:
Secret know-how
CommeR Statunts Regarding IPR Status:
The technology is patentable but not yet patented

Partner sought

Type and Role of Partner Sought:
The Italian researchers are interested in:
- Financial agreement to advance in the development of the technology;
- Research Cooperation Agreement to work together with another entity and to develop new solutions
- Technical cooperation agreement to implement the present technology and obtain a validated prototype to be tested in human subjects.
The ideal partner should have expertise/industrial interest in one or more of these fields: nutraceuticals, cosmeceuticals, functional food, food supplements, pharmacology.
It is highly request that the interested partner can bring own financial resource and share with the Italian group skills and technical resources to implement the technology.

Client

Type and Size of Client:
R&D Institution
Already Engaged in Trans-National Cooperation:
No
Languages Spoken:
English
Italian

Keywords

Technology Keywords:
08001002 Aditivos / ingredientes alimentarios / alimentos funcionales