Con esta herramienta te facilitamos un acceso a todas las ofertas y demandas de tecnología europeas y a búsquedas de socios para participar en propuestas europeas de I+D publicadas en la red Enterprise Europe Network, pudiendo filtrar los resultados para facilitar las búsquedas más acordes con tus necesidades.

¿Quieres recibir estos listados de oportunidades de colaboración en tu correo de forma periódica y personalizada? Date de alta en nuestro Boletín

Para optimizar los resultados de la búsqueda, se recomienda utilizar términos en inglés.

Estructura polimérica microporosa única obtenida mediante un proceso de fabricación especial

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TODE20190227001
Publicado:
06/03/2019
Caducidad:
05/03/2020
Resumen:
Investigadores de una universidad alemana han inventado una estructura polimérica microporosa única con canales totalmente reticulados mediante un proceso especial de fabricación controlado por plantillas. Esta estructura específica de microcanales puede utilizarse para descontaminar lentes de contacto y reservas de agua, etc. y eliminar patógenos como Acanthamoeba castellanii. Estos parásitos pueden incluso capturarse dentro de la red de microcanales y eliminarse del medio de incubación mediante la poliacrilamida porosa, lo que indica el alto potencial de la nueva técnica para aplicaciones médicas, farmacéuticas y de ingeniería de tejidos. La universidad, que ha solicitado la patente, busca una empresa o centro de investigación en Europa con el fin de establecer acuerdos de licencia con asistencia técnica.

Details

Tittle:
Unique microporous polymer structure through a special manufacturing process offered for a license agreement
Summary:
Researchers of a German university invented a unique microporous polymer structure with completely crosslinked channels through a special, template-controlled manufacturing process. This specific structure of micro-channels can be used to decontaminate contact lenses cases and water reservoirs etc. from pathogens such as Acanthamoeba castellanii.
A company or a research institution is sought in Europe for a license agreement with technical assistance.
Description:
A group of researchers of a German university developed novel microstructured 3D hydrogels for control of cellular mechanotransduction. Mechanotransduction is a process of transferring mechanical signals into cellular reactions. It has great impact on cellular activity by modifying their proliferation, migration, differentiation and cell adhesion. These cellular properties are also influenced by the 3D architecture of their extracellular environment. The research results present a highly attractive 3D interconnected micro-channeled soft biomaterial to mimic architecture and mechanical properties of the natural cellular environment and thus to control cellular mechanotransduction pathways. The fabrication process is based on hydrolyzing micrometer-sized tetrapods within a hydrogel, leading to hollow interconnected channels inside the hydrogel. The material possesses unique features such as a high micropore fraction >75 vol% as well as adoptable mechanical properties of the hydrogel. The specific structure and size distribution of micro channels in the 3D hydrogel can also be used for decontamination of e.g. contact lenses cases and water reservoirs from pathogens such as Acanthamoeba castellanii.These parasites can even be captured inside the microchannel network and were removed from their incubation medium by the porous polyacrylamide, indicating the huge potential of the new technique for medical, pharmaceutical and tissue engineering applications.
For this new methodology, a patent is applied for. To open up the market for this procedure the university offers its invention for a license agreement with technical assistance to research-oriented companies in Europe.
Advantages and Innovations:
The invented 3D material has the following advantages and innovations:

- can capture cells
- can be fabricated in different levels of complexity
- can be fabricated using high-throughput processes
- excellent control on cells
Stage of Development:
Prototype available for demonstration
IPs:
Patent(s) applied for but not yet granted
CommeR Statunts Regarding IPR Status:
A unique feature offered by the fabrication procedure for which the university has applied for a patent (EP 15166793.8, PCT/EP2016/060160).

Partner sought

Type and Role of Partner Sought:
The university is looking for a research-oriented company with infrastructure and know-how to jointly develop marketable concepts for novel products or for a partner to transfer the knowledge into already existing products.
It is also looking for a company involved in applications that range from 3D cell cultures to implant materials.
The university wants to commercialize the process for a licence agreement with technical assistance.

Client

Type and Size of Client:
University
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English
German

Dissemination

Restrict dissemination to specific countries:
Austria, Belgium, Bulgaria, Croatia, Czech_Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Macedonia, The Former Yugoslav Republic Of, Malta, Netherlands, Poland, Portugal, Republic of Serbia, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey, Ukraine, United Kingdom

Keywords

Technology Keywords:
06001003 Citología, cancerología, oncología
05005 Micro y nanotecnología
06004 Micro y nanotecnología relacionada con las ciencias biológicas