Con esta herramienta te facilitamos un acceso a todas las ofertas y demandas de tecnología europeas y a búsquedas de socios para participar en propuestas europeas de I+D publicadas en la red Enterprise Europe Network, pudiendo filtrar los resultados para facilitar las búsquedas más acordes con tus necesidades.

¿Quieres recibir estos listados de oportunidades de colaboración en tu correo de forma periódica y personalizada? Date de alta en nuestro Boletín

Los términos de búsqueda han de ser en inglés.

Ferrofluidos acuosos con calentamiento magnético mejorado para hipertermia

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOES20170220001
Publicado:
30/03/2017
Caducidad:
30/03/2018
Resumen:
Un centro de investigación español ha desarrollado ferrofluidos acuosos en los que las nanopartículas magnéticas se dispersan en agua mediante el uso de un biopolímero. Estos ferrofluidos se obtienen con un método en un solo paso que da lugar a dispersiones estables coloidales por períodos de 6 meses a pH fisiológico. Gracias a sus valores de calentamiento magnético mejorados, los ferrofluidos están indicados para terapia de hipertermia. Su alto poder específico de absorción (SPA) permite un calentamiento magnético de 17º C en solo 90 segundos cuando se aplica un campo magnético de 300G y 440kH. El centro de investigación busca socios industriales de los sectores farmacéutico, médico o químico con el fin de establecer acuerdos de licencia de la patente.

Details

Tittle:
Aqueous ferrofluids with improved magnetic heating for hyperthermia
Summary:
A Spanish Research Institution has developed aqueous ferrofluids where magnetic nanoparticles are dispersed in water using a biopolymer as a dispersing agent. They are obtained in a one-step method giving rise to stable colloidal suspensions for periods up to 6 months at physiological pH. Due to their enhanced magnetic heating they are suitable for hyperthermia therapy.
Industrial partners in pharmaceutical, biomedical or chemical sector are being sought for a patent license agreement.
Description:
Ferrofluids hold great potential for application in biomedicine. Most methods to produce ferrofluids involve more than one-step and give rise to dispersions with short-term colloidal stability. When using biopolymers as dispersing agents, an additional difficulty is encountered since there are no standardized methods for determining their molecular weight. This fact prevents a true control and reproducibility of the production method due to the great variability of the starting biopolymers.
A public Spanish research organization specialized in polymers has developed these new ferrofluids consisting of a colloidal dispersion of iron nanoparticles in water using sodium alginate as dispersing agent. Synthesis and stabilization of these nanoparticles are achieved through a one-step method in mild conditions. The high specific power absorption (SPA) of these ferrofluids allows magnetic heating of 17ºC in just 90 s under an applied magnetic field of 300G and 440kHz. Besides, due to their improved stability at physiologic pH and their small particle size (~8 nm), these ferrofluids are suitable for intravenous administration. These materials are suitable for application in hyperthermia therapy.

These ferrofluids have been patented. As a public research organization, the applicant doesn´t carry out commercial exploitation of this technology. It is looking for companies in pharmaceutical and/or chemical sector interested in a license agreement for commercial exploitation of it.
Advantages and Innovations:
-Synthesis and stabilization of nanoparticles is carried out in a one-step method in mild conditions.
-Their high SPA rates allow rapid magnetic heating.
-Their small particle size together with their long-term colloidal stability and the presence of a biopolymer as a dispersing agent, inherently biocompatible and biodegradable, enable the intravenous administration of these ferrofluids.
-These ferrofluids are suitable for hyperthermia therapy
Stage of Development:
Available for demonstration
IPs:
Patent(s) applied for but not yet granted
CommeR Statunts Regarding IPR Status:
Priority patent application filed suitable for international extension

Partner sought

Type and Role of Partner Sought:
Industrial partners, in particular from pharmaceutical, chemical and biomedical sector, or manufacturers of speciality materials interested in a license agreement for further development and exploitation of the technology.

Client

Type and Size of Client:
R&D Institution
Already Engaged in Trans-National Cooperation:
No
Languages Spoken:
English
Spanish

Keywords

Technology Keywords:
02007014 Plastics, Polymers