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Low-power atmospheric cold plasma source for cornea infections treatment.

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOIT20210428003
Publicado:
23/11/2021
Caducidad:
24/11/2022
Resumen:
An Italian research and innovation Institute has developed an innovative cold plasma (ionized gas at ambient temperature) source for biomedical applications, suitable for the treatment of diseases even of extremely sensitive tissues, such as the cornea. The plasma treatment promotes both disinfection and wound healing. Collaboration is sought under license agreement or financial agreement, for the certification of the prototype and its development towards the market.

Details

Tittle:
Low-power atmospheric cold plasma source for cornea infections treatment.
Summary:
An Italian research and innovation Institute has developed an innovative cold plasma (ionized gas at ambient temperature) source for biomedical applications, suitable for the treatment of diseases even of extremely sensitive tissues, such as the cornea. The plasma treatment promotes both disinfection and wound healing. Collaboration is sought under license agreement or financial agreement, for the certification of the prototype and its development towards the market.


Description:
In collaboration with an academic Institute, an Italian research and innovation Institute, based in North East and with a recognized experience and know how in the field of plasma physics and technology for applicative purposes, has developed a new technique for the generation of an atmospheric cold plasma (ionized gas) for the treatment of extremely sensitive biological tissues.
In the source, a flow of noble gas is ionized by means of a radiofrequency applied electric field at extremely low power levels. This technique guarantees that the ionized gas remains at room temperature, while the presence of a population of free electrons, when mixing with ambient air, induces the formation of reactive oxygen species, responsible for the biological effect.
The technique can be applied for the treatment of infected ulcers as well as to induce healing of chronic wounds. In particular, the plasma is suitable for infectious corneal diseases, which are the main responsible for blindness in the world.
The proposed technology is oriented towards hospitals and medical offices of health. Quality and safety certification of the prototype as medical instrument is needed, along with clinical trials to be performed in collaboration with medical institutions.
The technology must then be developed at an industrial level, and brought to the market by companies manufacturing tools for biomedical applications.
The institute is looking for partners to cooperate under license agreement for the realization of the final prototype to be certified, with technical assistance, to meet the market´s standards, or under financial agreement, to support the certification process and the industrial and commercial development.
Advantages and Innovations:
The main advantage of this plasma source with respect to existing ones for medical applications is associated with the way the plasma is produced, which implies that no electrical current and no related Ohmic heating are induced on the biological tissue to be treated. The main therapeutic effect of the plasma source comes from the active chemical species generated by the plasma itself.
The new technique has been successfully applied on in-vitro as well as ex-vivo infections on human and animal corneas, but it has also shown to promote wound healing in in-vivo experiments on large animals.


Stage of Development:
Available for demonstration
IPs:
Secret Know-how,Patents granted,Exclusive Rights
CommeR Statunts Regarding IPR Status:
European and International Patents granted.

Partner sought

Type and Role of Partner Sought:
Type: the institute is looking for industrial partners interested in a low-power atmospheric cold plasma source, for the treatment of diseases even of extremely sensitive tissues, such as the cornea.
Field of Activity: any kind of manufacturing involving biomedical instruments.
Role of partner sought: companies in the field of biomedical instruments for the realization under license agreement of the final prototype to be certified, with technical assistance, towards the market, or financial agreement with the proposing institute for financial support of the certification phase, industrial and commercial development.

Client

Type and Size of Client:
R&D Institution
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English
Italian

Keywords

Technology Keywords:
06002002 Biología celular y molecular
06001002 Investigaciones clínicas, ensayos
07001009 Medicina veterinaria
06002008 Microbiología
06001013 Tecnología médica / ingeniería biomédica