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Microchips funcionalizados porosos obtenidos mediante impresión 3D

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOES20170403001
Publicado:
30/05/2017
Caducidad:
30/05/2018
Resumen:
Un centro de investigación español ha desarrollado microchips obtenidos mediante impresión 3D que consisten en reservorios simples o múltiples que se conectan con superficies funcionalizadas porosas. El método de obtención permite diseñar en un solo paso microdispositivos con un control preciso de la funcionalidad. Estos microchips están disponibles para demostración. Los microchips se obtienen mediante impresión 3D, ofreciendo una amplia versatilidad en cuanto al diseño del circuito. El centro de investigación busca fabricantes de dispositivos de laboratorio para biotecnología y diagnóstico interesados en la licencia de la patente.

Details

Tittle:
Porous functional microchips obtained by 3D printing
Summary:
A Spanish research institution has developed microchips obtained by 3D printing that consist in single or multiple interconnected reservoirs with porous functional surfaces. The method of obtention enables to design in one single step microdevices where a precise control of functionality is achieved. These microchips are available for demonstration. A patent has been filed. A patent license is offered to manufacturers of laboratory devices for life sciences and diagnostics companies.
Description:
Lab-on-a-chip are systems that integrate several laboratory functions on a single microfluidic device enabling the sequential performance of several processes. Currently, the production of these devices involves several stages giving rise to a complex and expensive manufacturing process. Besides, regarding to functionality, a precise control and wide versatility is not allowed.
Microfluidic device developed by a Spanish research organization contains reservoirs with porous functional surfaces. The production process allows to obtain in one single step pores with a precise control of functionality. Functional groups include diethylamine, primary amines, acids groups or cyclodextrin (CD). For example, microdevices where pores contain CD groups have been obtained; these groups are able to form a complex with enzymes modified with adamantane. Likewise, other biomolecules such as nucleic acids, antibodies, adhesion proteins, fluorophores, chromophores or sensor molecules can be anchored. These results demonstrate the suitability of these devices for enzymatic catalysis or for the production of sensors for biomedical application.
As a public research organization, the applicant doesn´t carry out commercial exploitation of this technology. It is looking for manufacturers of laboratory devices for life sciences and diagnosis interested in a license agreement for commercial exploitation of this technology.
Advantages and Innovations:
Microchips can be obtained by 3D printing allowing a wide versatility in circuit designs.
Reservoirs with tailored functional porous surface can be achieved according to the application. Pores can contain one or more functional groups.
A higher surface area is achieved due to the porous surface enabling an improved catalytic activity, detection response, etc. in accordance to the target application. The catalytic activity of these microchips has been tested being 20 times better than that of other known systems.
Stage of Development:
Available for demonstration
IPs:
Patent(s) applied for but not yet granted
CommeR Statunts Regarding IPR Status:
Priority patent application filed suitable for international extension

Partner sought

Type and Role of Partner Sought:
Manufacturers of lab-on-a-chip for life sciences and diagnostics companies
The partner should be interested in a license agreement for further development of a particular application and commercial exploitation of the technology.

Client

Type and Size of Client:
R&D Institution
Already Engaged in Trans-National Cooperation:
No
Languages Spoken:
English
Spanish

Keywords

Technology Keywords:
06002002 Biología celular y molecular
05005 Micro y nanotecnología
02007014 Plastics, Polymers
06002003 Tecnología de enzimas