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Nueva composición para el tratamiento de enfermedades neurodegenerativas, como el párkinson

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOES20190404004
Publicado:
08/05/2019
Caducidad:
08/05/2020
Resumen:
Un grupo de investigación español del Sistema Nacional de Salud ha desarrollado una nueva composición para prevenir, aliviar, mejorar y tratar enfermedades o trastornos relacionados con la enfermedad de Parkinson. La composición tiene en cuenta la función importante del sistema nervioso entérico en la patogénesis de la enfermedad de Parkinson y la conexión entre enfermedades intestinales inflamatorias y la flora bacteriana. Esta conexión supone la creación de una nueva composición que consiste en al menos un aminosalicilato como principio activo. El uso de la composición es preventiva: la administración se realiza antes del diagnóstico de la enfermedad o en las primeras etapas. El grupo de investigación busca socios con el fin de establecer acuerdos de licencia o cooperación técnica para continuar con el desarrollo de esta composición patentada.

Details

Tittle:
New composition for the treatment of neurodegenerative diseases like Parkinson
Summary:
A Spanish research group of the public health system has developed a new composition to prevent, alleviate, ameliorate and treat diseases or disorders related to Parkinson´s disease.
A license agreement or an technical cooperation agreement for a public or private partnership for the further development of the patented composition is sought.
Description:
Neurodegenerative disease is an umbrella term for a range of conditions which primarily affect the neurons in the human brain. Neurons are the building blocks of the nervous system which includes the brain and spinal cord. Neurons normally do not reproduce or replace themselves, so when they become damaged or die they cannot be replaced by the body. Examples of neurodegenerative diseases include Parkinson´s, Alzheimer´s, and Huntington´s disease.

A Spanish hospital research group has developed a new composition to prevent, alleviate, ameliorate and treat diseases or disorders specially related to Parkinson´s disease. The composition takes into account the relevant role of the enteric nervous system in the pathogenesis of Parkinson´s disease (PD) and the connection between inflammatory intestinal diseases and bacterial flora. This connection supposes a new composition that consists of at least one aminosalicylate as active ingredient.

The use of the composition is preventive: the administration is carried out before the diagnosis of the disease, or in the first stages.


The research group is looking for the following collaboration:
-License agreement: framework of authorizing the interested parties to use the technology.
-Technical cooperation agreement: to collaborate with other research teams, companies or foundations.
Advantages and Innovations:
- The connection between inflammatory intestinal diseases and bacterial flora suppose a new composition that can be used to prevent, alleviate, ameliorate and treat Parkinson´s disease.

- The composition acts as a protective factor by preventing the spread of alfa synuclein in the intestine as a result of a
modification in the bacterial flora when the patient is
suffering an intestinal inflammation.

- It is possible to use this composition with others drugs as a
combination therapy.
Stage of Development:
Available for demonstration
IPs:
Patent(s) applied for but not yet granted
CommeR Statunts Regarding IPR Status:
PCT patent application

Partner sought

Type and Role of Partner Sought:
The research group aims to formalize a technology transfer process through a license agreement. The potential partner can be public or private entities interested in the implementation of the solution. The company is already selling the technology in Spain and now they are open to establish agreements with both European and non-European companies.

If there are some entities, such as R-Y-D centres, technology centres or specialized companies, interested in collaborating and developing further aspects of the solution, a technical cooperation agreement could be envisaged. They can also be European or non-European entities.

Client

Type and Size of Client:
R&D Institution
Already Engaged in Trans-National Cooperation:
No
Languages Spoken:
English
Spanish

Keywords

Technology Keywords:
06001010 Gerontología y geriatría
06001012 Investigaciones médicas
06001014 Neurología, investigación cerebral
06001013 Tecnología médica / ingeniería biomédica