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Nueva preparación para el tratamiento de enfermedades fúngicas de la piel

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOAM20160412001
Publicado:
18/05/2016
Caducidad:
18/05/2017
Resumen:
Una empresa farmacológica armenia ha desarrollado una nueva preparación multicomponente para el tratamiento de enfermedades fúngicas de la piel. Esta preparación tiene propiedades antifúngicas y antibacterianas muy eficientes contra varios microorganismos. La preparación contiene ácido acético, hexametilenetetramina, fosfatidilcolina, acetato de tocoferilo y glicerol. Todavía no se ha llevado a cabo el estudio in vivo de las propiedades antibacterianas y antifúngicas de la preparación. La empresa busca socios con el fin de establecer acuerdos de cooperación técnica, financiación y fabricación.

Details

Tittle:
Innovative anti-fungal preparation for treatment of skin fungal diseases.
Summary:
An Armenian pharmacological company has developed a new multi-component preparation for treatment of skin fungal diseases, which has high efficient antifungal and antibacterial properties against various microorganisms. The in vivo study of antibacterial and antifungal properties of the preparation has not been performed yet. The company is looking for technical cooperation agreement, financial agreement and manufacturing agreement.
Description:
Established in 2014, the company is engaged in development and production of pharmaceuticals. Currently the company is in the stage of developing of a new antifungal preparation. It is a multi-component liquid preparation, which was developed and patented as topical antifungal agent. Preparation contains acetic acid, hexamethylenetetramine, phosphatidylcholine, tocopheryl acetate and glycerol. This preparation does not have any noticeable toxicity and does not express any side effects. According to the preliminary data the preparation showed high membrane stabilizing properties on experimental animals. It also expresses antioxidant activity which is partially connected with its phosphatidylcholine and tocopheryl acetate components. The investigations showed high antimicrobial activity the preparation has against various tested bacterial, yeast and mould strains. Fungal skin infections are considered as one of the urgent challenges of medicine due the lack of efficiency of commonly used antifungals, which also are very expensive. In contrast, the new preparation showed high efficiency, has not shown observable toxicity on skin and its components are not expensive, it can be advantageous for management of various skin medical conditions.
The company seeks partners for technical cooperation agreement to proceed with in vivo study of antibacterial and antifungal properties of the preparation, financial agreement to investigate antibacterial and antifungal properties of the preparation against causative agents of various skin infections. The purpose is also to study the biochemical mechanisms of the preparation´s action during treatment of fungal and bacterial skin infections on experimental animals to develop new antimicrobial drug. The company is also interested in finding partners for manufacturing agreement to develop new antimicrobial drug and its further manufacturing.
Advantages and Innovations:
This new preparation is the improved version of the previous preparation, which was on the market. Now, two new components (phosphatidylcholine and tocopherol acetate) are added to raise its efficiency to suppress lipid peroxidation processes and accelerate the cells regeneration at the infected sites. The new preparation has broad range of activity against various bacterial and fungal infectious agents which has been shown in previous works. The majority of current superficial medicines which currently are being used for the treatment of skin fungal and bacterial diseases are prepared on ointment form. This considerably reduces absorption of preparation on the infected skin area and, therefore, reduces its therapeutic efficiency. In contrast to this, the new preparation is a liquid one and characterized high absorption rate. It is a complex preparation consisting of several compounds with defined ratio providing its high activity and broad range.
Stage of Development:
Available for demonstration
IPs:
Patents granted

Partner sought

Type and Role of Partner Sought:
The company is looking for partners to proceed the preclinical trials of this preparation as superficial antimicrobial preparation for treatment of various skin infections, as well as manufacturing of new antimicrobial drug and investment of it in practical medicine. The companies engaged in pharmaceutical sphere (the producers of medicine, the companies engaged in sale of medicine, etc.)

Client

Type and Size of Client:
Industry SME <= 10
Already Engaged in Trans-National Cooperation:
No
Languages Spoken:
English
Russian

Keywords

Technology Keywords:
06001002 Investigaciones clínicas, ensayos
06001012 Investigaciones médicas
06002008 Microbiología
06001015 Productos farmacéuticos / medicamentos
06001018 Virus, virología / antibióticos / bacteriología