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Nuevo sistema de administración y doble encapsulación para la administración oral de medicamentos/moléculas bioactivas

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOFR20151117003
Publicado:
08/12/2015
Caducidad:
08/12/2016
Resumen:
Un centro privado francés de investigación especializado en diabetes ha desarrollado y obtenido la patente de una nueva tecnología de doble nanoencapsulación de moléculas bioactivas para administración oral, síntesis, biodisponibilidad (cruce de la barrera intestinal) y estudios de toxicidad. Se buscan pymes, centros de investigación, socios académicos y usuarios finales en áreas sanitarias y con experiencia en nanoformulaciones para establecer acuerdos de cooperación técnica, investigación o licencia.

Details

Tittle:
Innovative double encapsulation delivery system for an oral administration of drugs/bioactive molecules (proof of concept in the field of diabetes)
Summary:
A French private research organisation specialised in diabetes, developed and patented an innovative double nano-encapsulation technology of bioactive molecules for oral administration, whole vehicle synthesis bioavailability (e.g. intestinal barrier crossing) and toxicity studies.
They are looking for SMEs, Research Centres, Academics, End Users, from any health areas and expert in nano-formulation, for technological, research or licence agreement.
Description:
The private research organisation developed and patented an innovative technology based on a double encapsulation delivery system.
They developed a vector for oral administration of at least one pharmacologically active substance that allows passage from the lumen of the intestines into the blood, optionally through interstitial fluid, without significant denaturation or degradation of the substance. It comprises an essentially hydrophilic matrix having an outer surface, which is modified by one or more chemical species that confer lipophilicity to the vector.

Main activities:
- Assessment of biological properties in the field of diabetes and associated complications (in vitro cellular, in vivo diabetic rat models)
- Nanoencapsulation of bioactive molecules for oral administration, whole vehicle synthesis,
- Nano-Particles (NPs) physico-chemical characterization / Stability studies
- Bioavailability studies (e.g. intestinal barrier crossing)

Applicable to various health areas.

They are willing to share this expertise with structures (SMEs, Research centres, Universities) involved in different health areas and are ready to integrate European projects.
Advantages and Innovations:
Innovative double encapsulation delivery system (patented) allowing oral administration of drugs by protecting them from the digestive tracts while facilitating intestinal absorption.
Stage of Development:
Available for demonstration
IPs:
Secret Know-how,Patents granted
CommeR Statunts Regarding IPR Status:
PCT Patent

Partner sought

Type and Role of Partner Sought:
Type : SME, Research Centre, Academics, End Users

Areas of activity :
- Biological functionality in diabetes and other health area (e.g. coagulation field/oral heparin, antioxidant molecules from food)
- Nanoformulation (biopolymers, excipients) / nanoparticle toxicity
- Nutrition
- SME with drugs/bioactive molecules to encapsulate for oral administration
- Industrial technology transfer/scale-up

Role :
- Integrate the technology developed
- Exchange upon new development opportunities

Client

Type and Size of Client:
Industry SME 11-49
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English
French

Keywords

Technology Keywords:
06004 Micro y nanotecnología relacionada con las ciencias biológicas
08003 Micro y nanotecnologías relacionadas con la alimentación
06006006 Nanomateriales biológicos
06001015 Productos farmacéuticos / medicamentos
06001013 Tecnología médica / ingeniería biomédica