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Nuevos apósitos basados en biopolímeros

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOLT20160503001
Publicado:
20/05/2016
Caducidad:
20/05/2017
Resumen:
Una universidad lituana ha desarrollado nuevos apósitos de biopolímero en película o esponja para el tratamiento de diferentes tipos de heridas. Estos apósitos se preparan con polímeros naturales, biocompatibles y no citotóxicos, como celulosa regenerada, alginato de sodio, pectina, hidroxietilcelulosa y ácido hialurónico, mediante diferentes técnicas. Las características físico-químicas, como capacidad de absorción de exudado, permeabilidad al vapor de agua, adhesión a la superficie de la herida y propiedades mecánicas, cumplen los requisitos de los apósitos para el cuidado de heridas. Las tecnologías se encuentran en fase experimental. La universidad busca cooperación en materia de investigación y recursos financieros.

Details

Tittle:
The technologies of innovative wound dressing, research cooperation and financial resources are sought.
Summary:
A Lithuanian University has developed new biopolymer-based wound dressings in film or sponges form targeted for treating of different kind of wounds. The technologies are developed at laboratory scale. Research cooperation and financial resources are sought.
Description:
Recently, a new generation of wound dressings has been extensively developed. Dressings made of new forms such as sponges, films and hydrocolloids have been developed together with new functions. Modern bandages not only protect the wound from infection, but as well promote the healing process, irrigate the wound, absorb the wound secretions, achieve the desired pH of the wound medium, stimulate the necessary growth factors and carry active compounds into the wound. Therefore, it is very important to perform a variety of chemical investigations.
Scientists at a Lithuanian University have developed new biopolymer-based wound dressings They are prepared from natural, biocompatible, non-cytotoxic polymers, such as regenerated cellulose, sodium alginate, pectin, hydroxyethylcellulose as well as hyaluronic acid by means of different techniques. The materials proposed are targeted for treating of different wounds. In a case of burn or open wounds transparent films from regenerated cellulose (non-adherent and non-absorbed) and hyaluronic acid (totally absorbed) have been developed. For chronic wounds with high level of exudate sponges-like dressings are prepared. For deep wound, for example for teeth cavities, resorbable sponges have been developed. The physical-chemical characteristics, such as exudate absorption capacity, water vapour permeability, adhesion to wound surface, as well as mechanical properties meets the requirements for wound dressings. Also various active compounds, like antibiotics, flavanoids, povidone-iodine, furaciline were immobilized into the dressings.
The University is looking for:
- research cooperation with other universities and R-Y-D intitutions, whch are working in biomedical field;
- investors for financial resources for in vitro and in vivo trials.
- companies for futher development of the products.





Advantages and Innovations:
A wide variety of wound dressings:
- transparent cellulose hydrogel sheets which possess low bioadhesion and a high moisture content are promising wound dressings for burn wounds, cuts, scratches and abrasions;
- transparent fully resorbable hyaluronic acid films are promising for burn wounds;
- sponges from the mixture of water soluble biopolymers possess a high liquid absorption capacity and good blood clotting ability; thus, these sponges could be applied as wound dressings for exuding and bleeding wounds;
- hyaluronic acid sponges are resorbable, thus could be used in deep wound without their remowing.
All prepared dressing are not toxic, are not cytotoxic, are biocompatible.
Various active compounds, like antibiotics, flavanoids, povidone-iodine, furaciline, silver nanoparticles could be easily immobilized into the dressings.
Stage of Development:
Prototype available for demonstration
IPs:
Secret Know-how

Partner sought

Type and Role of Partner Sought:
Type of the partner sought:
- universities and R-Y-D institutions, which are working in biomedical field, for research cooperation;
- investors for financial resources for in vitro and in vivo trials.
- companies for further development of the products.
Research cooperation, license and financial agreements are sought.

Client

Type and Size of Client:
University
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English
Polish
Russian

Keywords

Technology Keywords:
06002007 Ensayos in vitro, experimentos
06001002 Investigaciones clínicas, ensayos