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Simulación de microgravedad y parcial mediante posicionamiento aleatorio

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TONL20160330001
Publicado:
18/04/2016
Caducidad:
18/04/2017
Resumen:
Una empresa holandesa especializada en investigación de microgravedad ha desarrollado una máquina de posicionamiento aleatorio (RPM) que genera microgravedad cambiando continuamente la orientación. De esta forma se generan efectos similares a los efectos de la microgravedad real (espacial). Un simple contenedor, que se conecta a dos ejes independientes, es girado por la máquina con velocidades aleatorias en todas las direcciones. Debido al movimiento aleatorio, la muestra experimenta la gravedad desde cualquier dirección. La empresa busca compañías de I+D en los sectores de biología, astrobiología y medicina regenerativa con el fin de establecer acuerdos comerciales con asistencia técnica.

Details

Tittle:
Partial- and microgravity simulation through random positioning
Summary:
A Dutch independent establishment of an international company offers microgravity research. They do this with a self-developed Random Positioning Machine (RPM), which provides microgravity by continuously changing the orientation. This generates effects similar to the effects of true microgravity (space).

The company is looking for research and development companies in life sciences, astrobiology and regenerative medicine for commercial agreements with technical assistance.
Description:
The Random Positioning Machine (RPM) of the Dutch company simulates micro-gravity. A sample container, which is connected to two independent axes, is rotated by the machine with random speeds in all directions. Due to the random motion, the sample experiences gravity from every direction. Thus, after some time the average of the gravity affecting the sample goes to zero. In this way, the RPM simulates microgravity for objects inside its container. This is sometimes also referred to as 3D clinostat.

Thanks to its versatility and quality the RPM is invaluable for research and development in many different fields, such as:
- Life science, cell biology and microbiology
- Astrobiology and planetary research
- Regenerative medicine, tissue engineering and stem cell research

Partial gravity
The RPM simulates ´partial gravity´. This provides all gravity levels from 0g up to 0.9g. Partial gravity is achieved by changing the random motion pattern in such a way that on average the sample experiences some influence of Earth´s gravity. It is used for simulating e.g. the 0.38g Mars´ gravity or 0.17g Moon´s gravity, but also for determining e.g. the gravity level at which organisms or cells change behaviour.

Life science, cell- and microbiology
Gravity has many important effects on cells and introducing microgravity allows new cell-, micro- and mechanobiology research. For example, microgravity leads to different intra- and inter-cell communication, changes in genetic expression, cell growth and shape, gravitropism and mechanosensitivity effects, etc.

Regenerative medicine, tissue engineering and stem cell research
Recently published papers describe the use of RPM for regenerative medicine and 3D tissue engineering / cell culturing. For example, research has shown that microgravity can be used to reduce differentiation of stem cells.

Astrobiology and planetary research
The partial gravity feature (0g - 0.9g) of the RPM is also very useful for astrobiology research. It is used to research organisms survival, development, behaviour etc. in extra-terrestrial environments such as the 0.38g Mars´ gravity and 0.17g Moon´s gravity. Furthermore, the instrument is involved in different control, pre- and post-experiments for the International Space Station (ISS). For example, microbiology is researched with the RPM since bacterial virulence and growth rate increase in microgravity.

The company is looking for research and development companies in life sciences, cell- and microbiology, astrobiology, regenerative medicine, tissue engineering, stem cell research, astrobiology and planetary research within the frame of commercial agreements with technical assistance.

Advantages and Innovations:
In comparison to prevailing techniques the Random Positioning Machine (RPM) enables micro- and partial gravity research for scientific, educational and industrial applications where experiments require a long-duration exposure to microgravity (hours, days, weeks).
Advantages of the RPM are:
- Unique and proven path algorithms with protection against pole bias.
- Advanced on-the-fly control and monitoring of experiments using fully integrated power and communication interfaces.
- Compact design to support experiments in incubator and radiation facilities.

The RPM provides a platform for mounting the experiment package, which is adjustable in height. The system is designed to operate inside an incubator for control of temperature, CO2 and relative humidity (non-condensing). Hardware and software are included to operate the RPM and to monitor its parameters, such as average g-level.
The RPM is a proven asset and valued by the scientific community as a simulation platform for micro- and partial gravity experiments. Moreover, the RPM is used for preparation and post-analysis of experiments that fly on the International Space Station.

Stage of Development:
Already on the market
IPs:
Secret Know-how,Copyright

Partner sought

Type and Role of Partner Sought:
Type of partner sought:
Universities, (R-Y-D) companies, institutes, hospitals, agencies.

Specific field:
Partner sought in one or more of the following research fields:
- Life science, cell biology or microbiology.
- Astrobiology or planetary research.
- Regenerative medicine, tissue engineering or stem cell research.

Role of partner:
Performs research and/or development in one of the above mentioned fields and is interested in exploring and applying the benefits of microgravity by using the Random Positioning Machine.

Client

Type and Size of Client:
Industry SME 50-249
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
Dutch
English

Keywords

Technology Keywords:
02011005 Exploración y tecnología espacial
09001002 Métodos e instalaciones de ensayo / análisis