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Soluciones basadas en una plataforma enzimática/microbiana para biocatálisis en las industrias química, alimentaria, farmacéutica y de materiales

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TODE20190423002
Publicado:
23/05/2019
Caducidad:
23/05/2020
Resumen:
Una pyme sino-alemana ofrece servicios integrales de I+D/comercialización y soluciones biocatalíticas mediante una plataforma enzimática y microbiana. Las enzimas, que funcionan como proteínas con un excelente rendimiento catalítico ecológico, ofrecen alternativas eficientes, ecológicas y seguras a la química tradicional e incluso pueden acortar considerablemente las rutas sintéticas. Sin embargo, la aplicabilidad de enzimas naturales como biocatalizadores suele ser reducida debido a su actividad limitada en sustratos poco naturales y a la inestabilidad en procesos industriales. La empresa ofrece soluciones que superan las limitaciones de las enzimas naturales en biocatálisis industrial. El paquete de servicios integrales de I+D y comercialización, desde la primera evaluación de las necesidades del cliente hasta el desarrollo industrial final, ofrecido por la empresa se lleva a cabo por un equipo de científicos altamente experimentados que aplican las últimas tecnologías vanguardistas. La empresa busca socios industriales/académicos en los sectores químico, alimentario, farmacéutico y de materiales para cooperar en actividades de I+D, por ejemplo, de nuevas rutas sintéticas para productos químicos especiales, productos de química fina y químicos farmacéuticos.

Details

Tittle:
Enzymatic/microbial platform technology offers solutions for biocatalysis for chemical, food, pharma and materials industry
Summary:
German-Sino SME provides all-in-one R-Y-D /commercialisation services and biocatalytic solutions via an enzymatic, microbial platform technology. It leads to major time savings, state of the art high throughput screening with 500,000 CPU (central processing unit) hours/year, high accuracy and consistency. They look for industrial/academic partners from chemical, pharma, food, home care, material industry for R-Y-D cooperation, e.g. new synthetic routes to speciality/fine/pharmaceutical chemicals
Description:
Traditional ways to produce pharmaceuticals and other chemicals often require environmentally unfriendly reagents and harsh conditions, such as heavy metals, corrosive acids and high temperatures.
Enzymes, functioning as proteins with green and excellent catalytic performance, offer efficient, eco-friendly and safe alternatives for traditional chemistry and can even significantly shorten synthetic routes.
However, the industrial applicability of natural enzymes as biocatalysts is often restricted by, for example, their limited activity on unnatural substrates and instability at industrial process conditions, such as the necessity of organic co-solvents and high substrate loadings.

A German-Sino company provides solutions which overcome the limitations of natural enzymes in industrial biocatalysis. The company provides an all-in-one R-Y-D and commercialization service package spanning from first assessment of customer´s needs to final industrial realization of developments. This whole process is guided by a team of highly experienced scientists from all over the world applying the latest state of the art technologies.

With their extensive experience in directed enzyme evolution, strain engineering, fermentation process development and commercial-scale biocatalytic production, they successfully apply a proprietary R-Y-D platform to develop novel, optimized enzyme technologies.

This enzyme directed evolution platform is spearheaded by the integration of bioinformatic database guided design, computer modelling and simulations, as well as state of the art high throughput screening systems.

Fields of application are fine chemical, pharmaceutical, food, personal and home care and material industries.
They are also exploring the development of biocatalysis technology for feed, environmental and waste treatment industries.

They look for industrial / academic partners from the fields mentioned above to offer enzyme technology solutions in the partner´s R-Y-D projects regarding, for example, new synthetic routes towards specialty, fine and pharmaceutical chemicals.

They also enable the optimization of the partner´s existing processes, by the optimization and/or implementation of enzymes.
The company is also open to other forms of cooperation.
Advantages and Innovations:
The proprietary enzyme engineering platform of the German-sino SME is a combination of two Nobel prize winning technologies (directed evolution and computational enzyme engineering), with the following key advantages:

- The application of bioinformatics-assisted design, simulations and analysis of protein mutations leads to major time savings and higher success rates within in the development of novel industrial enzymes.

- State of the art high throughput screening technologies and a supercomputer account with 500,000 CPU (central processing unit) hours/year allow for time efficient and parallel handling of up to six computer aided enzyme evolution projects.

- Automated and controlled laboratory procedures deliver higher accuracy and consistency of experimental results.

- The created novel enzymes provide unpreceded performance in nature, meet industrial applicability criteria and generate new intellectual property.

- The developed enzymatic processes have been proven to enable the manufacturing of diverse optically pure value-added products.
Stage of Development:
Already on the market
IPs:
Secret Know-how,Patent(s) applied for but not yet granted
CommeR Statunts Regarding IPR Status:
PCT application

Partner sought

Type and Role of Partner Sought:
They look for industrial/academic partners from the fields pharma, food and feed, chemistry, personal and home care as well as from materials for research and development cooperations.

Therein the company provides enzyme technology solutions in the partner´s R-Y-D projects regarding, for example, new synthetic routes towards specialty, fine and pharmaceutical chemicals.
However, optimization of the partner´s existing processes, by the optimization and/or implementation of enzymes is also possible

They are also open to other forms of cooperation.

Client

Type and Size of Client:
Industry SME 50-249
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
Chinese
English
German

Keywords

Technology Keywords:
06003001 Bioinformática
06006012 Bioprocesos
06006011 Fermentación
06002004 Ingeniería de proteínas
06002003 Tecnología de enzimas