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Start-up italiana que desarrolla tecnologías para la producción de dispositivos médicos con fibroína de seda 100% nano/micro estructurada para regeneración de tejidos in vivo busca socios tecnológicos e investigadores

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOIT20161205005
Publicado:
09/01/2017
Caducidad:
09/01/2018
Resumen:
Una start-up italiana del sector de regeneración de tejidos humanos ha desarrollado un nuevo dispositivo para la regeneración de pequeños vasos sanguíneos aprovechando las propiedades biomiméticas y ventajas mecánicas de la seda. La misma tecnología está indicada para diversas aplicaciones, como nervios periféricos, tendones y ligamentos y otros tejidos sometidos a tracción. Este nuevo dispositivo es más económico que otros injertos sintéticos, facilita la cirugía y evita la degradación peligrosa en el cuerpo del paciente. La empresa busca socios con el fin de establecer acuerdos de cooperación técnica e investigación y obtener la certificación ISO/FDA.

Details

Tittle:
Italian start-up developing technologies for the production of nano/micro structured 100% silk fibroin medical devices for in-vivo tissue regeneration is looking for technical and research partners.
Summary:
Italian start-up in the field of human tissue regeneration has developed a new device for the regeneration of small blood vessels by leveraging the biomimetic properties and the mechanical advantages of silk.
The same technology is suitable to several applications as peripheral nerves, tendons and ligaments, skin, and other tensile stressed tissues. The company is looking for partners for research and technical cooperation in the ISO/FDA approval pathway.
Description:
The offerer of the present technology is a medtech start-up whose first and main goal is to develop an innovative technology for the production of medical implantable devices made of silk fibroin for the in-vivo regeneration of human tissues and marketing it for human indications through licensing agreements. The technology is based on the coupling of electrospun matrices (ES) for boosting the biological and biomimetic properties of silk fibroin and textile matrices (TEXT) for the high mechanical tensile properties.
The company has designed a new device for the regeneration of small blood vessels. About 560k/year coronary artery bypass graft surgeries (CABG) are performed in OECD countries. The current golden standard for CABG is autograft (mainly saphenous vein, umbilical vein and mammary artery) and very often more than one graft is required for each procedure. However, autografts are not always available and present several drawbacks: so, there is a global urgent need for man-made grafts. Very few synthetic grafts are on the market and, due to their very poor results, they are used only when autografts previously failed. There is also a need for man-made solutions for peripheral blood vessels, like saphenous veins and carotids. For those vessels there are no autografts available and small calibre synthetic grafts fail in restoring the bloodstream. This innovative nanotechnology stimulates faster natural human tissue regeneration, with no rejection risks or use of drugs. In addition to that, it is cheaper than other synthetic grafts, allows for easy surgery and doesn´t produce any dangerous degradation product in the patient´s body.
In the developing pipeline other devices (peripheral nerves, tendons and ligaments, skin, dura madre, and other tensile stressed tissues) will be developed as soon as possible using the same technologies.
Different technologies are under investigation to further increase the addressable markets. This new technology lands in the tissue engineering market, which is worth globally -Y-euro;85bn.
The company has received and is receiving a number of VC funding and prizes which grant financial sustainability of the project; its goal now is to find a stable market for its new technology and explore other possible market applications.
The company is looking for strategic partners to further develop this technology, speed up the approval pathway, improve the investment readiness of the company, strengthen its long term sustainability, and develop new technologies based on the use of silk fibroin in biomed and biotech fields. Partners could be research or technical partners for support and cooperation in the ES-TEXT products development and validation; investigation and study of new technologies for biomed and biotech fields, interested in signing a research cooperation agreement and/or a technical cooperation agreement.
Advantages and Innovations:
This innovative device is cheaper than other synthetic grafts, allows for easy surgery and doesn´t produce any dangerous degradation product in the patient´s body.
Key opinion leaders, clinicians, venture capitalists and medical device companies have already recognized its commercial potential, which is estimated to be around -Y-euro;3.9bn annually in OECD countries.
Stage of Development:
Under development/lab tested
IPs:
Secret Know-how,Patent(s) applied for but not yet granted

Partner sought

Type and Role of Partner Sought:
The company is looking for strategic technical and research partners to further develop the ES-TEXT technology, speed up the approval pathway, improve the investment readiness of the company, strengthen its long term sustainability, and develop new technologies based on the use of silk fibroin in biomed and biotech fields. Partners could be research or technical partners for support and cooperation in the ES-TEXT products development and validation and investigation and study of new technologies for biomed and biotech fields (research cooperation agreement).

Client

Type and Size of Client:
Industry SME <= 10
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English
French
Spanish

Keywords

Technology Keywords:
06001002 Investigaciones clínicas, ensayos