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Suplemento dietético para prevenir la formación de productos finales de la glicación avanzada en pacientes diabéticos

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOES20151013003
Publicado:
13/01/2016
Caducidad:
13/01/2017
Resumen:
Investigadores de una universidad española han desarrollado y obtenido la patente de una composición dietética basada en fitato para prevenir la formación de productos finales de la glicación avanzada, sustancias tóxicas presentes en enfermedades como la diabetes. Esta nueva composición puede emplearse en el tratamiento o prevención de neuropatías, nefropatías, aterosclerosis, calcificación vascular y enfermedades neurodegenerativas. Se buscan empresas en los sectores de suplementos y nutrición para diabéticos con el fin de establecer acuerdos de licencia.


Details

Tittle:
Dietary supplement to prevent the formation of advanced glycation end products in diabetic patients
Summary:
Researchers from a Spanish university have developed and patented a dietary composition based on phytate to prevent the formation of advanced glycation end products (AGE), toxic substances present in diseases such as diabetes. Companies engaged in diabetic nutrition and supplementations interested in a license agreement are being sought.
Description:
Advanced glycation end products (AGEs) are substances resulting from the chemical reaction -an attachment, between a sugar molecule (as glucose) and an amino acid, most of which are harmful to people, especially for diabetics because of their higher glucose levels. These substances can be a factor in the development or worsening of many degenerative diseases, such as diabetes, chronic renal failure or Alzheimer´s disease. In diabetes, AGEs are the responsible for microvascular and macrovascular complications (nephropathy, neuropathy).

Phytate is a natural product presents in our diet (legumes and cereals) which is demonstrated to have an important inhibitory effect on AGEs formation. Interestingly, diabetic patients follow a diet low in rich-phytate foods and their physiological levels of phytate are extremely low. For these reasons, a supplementation of phytate would be very important in order to avoid or retard future complications in these patients

Spanish researchers specialized in the field of renal lithiasis and nutrition have developed a new composition based on phytate and vitamers to prevent the formation of AGEs, so that they can be used therapeutically in the treatment or prevention of diseases such as neuropathy, nephropathy, atherosclerosis, vascular calcification and neurodegenerative diseases.

Companies engaged in diabetic nutrition interested in a license agreement for developing a supplement are being sought.
Advantages and Innovations:
One of the therapeutic approaches is preventing the formation of AGE through inhibitors. One of these inhibitors is the Metformin. As an alternative, the developed dietary composition is based on natural products -phytate and vitamin B6, avoiding adverse effects to health and having a high inhibitory capacity for the formation of AGE.
Stage of Development:
Available for demonstration
IPs:
Patent(s) applied for but not yet granted
CommeR Statunts Regarding IPR Status:
Patent application filed recently in Spain (priority) with the possibility to file an international application (PCT).

Partner sought

Type and Role of Partner Sought:
Companies engaged in diabetic nutrition interested in a license agreement for developing a supplement are being sought.

Client

Type and Size of Client:
University
Already Engaged in Trans-National Cooperation:
No
Languages Spoken:
English
Spanish

Keywords

Technology Keywords:
08001002 Aditivos / ingredientes alimentarios / alimentos funcionales