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Tecnología basada en probióticos para tratamiento de la mastitis

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOIE20151019001
Publicado:
21/10/2015
Caducidad:
20/10/2016
Resumen:
Un instituto de investigación irlandés ha desarrollado un nuevo enfoque biológico para la prevención de la mastitis basado en cultivos vivos de grado alimentario de bacterias probióticas, específicamente una cepa de lactococcus lactis eficaz en el tratamiento de enfermedades infecciosas de humanos y animales. Esta cepa ha demostrado ser al menos igual de eficaz que los antibióticos en el tratamiento de la mastitis y es efectiva contra la mastitis causada por bacterias Gram positivas y Gram negativas. Se buscan socios comerciales dentro de la industria veterinaria interesados en licenciar la tecnología.

Details

Tittle:
Probiotic based technology for the treatment of mastitis
Summary:
An Irish research institute has developed a novel technology which represents a biological approach to mastitis prevention and is based on live food grade cultures of probiotic bacteria, specifically a proprietary strain of Lactococcus lactis, effective in treating animal and human infectious diseases and proven to be at least as effective as antibiotics, in the treatment of mastitis. Commercial partners within the animal health industry interested in licensing this technology are being sought.
Description:
Current treatments for mastitis rely heavily on antibiotics, both for prophylaxis and therapy. This strategy is costly and frequently ineffective. Additionally there are concerns regarding the overuse of antibiotics in veterinary medicine, as it may contribute to the increased spread of antibiotic resistance to human and animal pathogens. Recent legislation in the EU curtailing the use of antibiotics in animal feed should lead to greater controls and limitations in their use. Use of antibiotics may be limited to situations where they are deemed critical.

There are several advantages to this treatment regime. The bacterium can be produced cheaply in large quantities and it is a foodgrade organism with GRAS (Generally Recognised As Safe) status and hence should not require significant withholding periods for the milk produced by recovering animals, as in the case of treatment with antibiotics.

The Irish Research Institute responsible for this technology is a well-established national body in the agri-food sector which supports science-based innovation and the wider bioeconomy. Suitable partners within the animal health industry are being sought through a licence agreement.
Advantages and Innovations:
The technology provides the following key benefits;

1. Natural, effective alternative to antibiotic therapy for treatment of both mild and severe mastitis. Effective against mastitis caused by gram positive and negative bacteria.

2. Using live preparation, cure rates of subclinical and clinical infections were comparable to standard antibiotic therapy.

3. Based on use of a food grade organism, significant withholding periods should not be required for milk produced by recovering animals, thereby reducing milk losses.

4. Could improve milk quality from clinically infected quarters.
Stage of Development:
Under development/lab tested
IPs:
Patents granted
CommeR Statunts Regarding IPR Status:
Patent granted in the United States of America and in selected European countries.

Partner sought

Type and Role of Partner Sought:
Seeking a commercial partner within the animal health industry interested in licensing a novel technology involving the treatment of bovine mastitis with food grade probiotic bacteria - a natural and effective alternative to antibiotic therapy.

Client

Type and Size of Client:
R&D Institution
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English

Keywords

Technology Keywords:
07001001 Maquinaria agrícola / tecnología
07001009 Medicina veterinaria
07001010 Micro y nanotecnologías relacionadas con la agricultura
06001018 Virus, virología / antibióticos / bacteriología