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Tecnología de perfilado de metabolitos y biomarcadores

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TODE20150928001
Publicado:
08/01/2016
Caducidad:
08/01/2017
Resumen:
Una empresa alemana de biotecnología ofrece servicios de investigación y analíticos en el campo de perfilado de metabolitos. Su actividad de investigación bioquímica se centra en perfilado de metabolitos y lipidómica en sistemas biológicos y mejora cualitativa de la vida combinando enfoques analíticos y grandes archivos de datos. La empresa analiza metabolitos conocidos y desconocidos en una muestra mediante el uso de tecnologías avanzadas de espectrometría de masas. Se buscan socios en los sectores de farmacia, biotecnología o alimentación con el fin de establecer acuerdos de investigación o servicio.


Details

Tittle:
German biotechnology SME offers metabolite profiling and biomarker technology
Summary:
A German biotechnology company offers research and analytical services in the field of metabolite profiling. Their biochemical research is focused on metabolite profiling and lipidomics in biological systems and the qualitative improvement of life by combining analytical and big data approaches. The company would like to work together through a research cooperation or a services agreement.
Description:
The German small biotechnology business is an analytical service and research company. They support clients from various industries by resolving complex biological related questions using an untargeted metabolomics platform (a permanent laboratory set-up analysing as many metabolites as possible, instead of selecting particular metabolites).
Metabolomics is the systematic study of chemical processes involving metabolites, the set of life-sustaining chemical transformations within the cells of living organisms. Furthermore, profiling metabolites of pharmaceutical compounds is an important part of drug discovery.
The metabolomics platform is able to perform several analyses. Put together, they provide a full understanding of metabolite processes:

First, the company provides high-resolution, accurate mass-spectrometry-based metabolite profiling. Mass spectrometry is an analytical chemistry technique that helps identify the amount and type of chemicals present in a sample by measuring the mass-to-charge ratio and abundance.

Next to high-resolution mass-spectrometry, the company uses advanced bioinformatics to identify patterns and biomarkers. They provide analyses of microbes, body fluids, animal tissues, complex fluids, plants, food and beverage. The advanced bioinformatics platform provides insights into cellular mechanisms. The platform integrates genome, transcriptome and any other -omics data to identify networks and correlations between phenotypes and genotypes. The machine and deep learning tools unravel metabolic patterns and biomarker for diagnostics.

Contrary to competitors, the company can provide not only insight into untargeted and targeted approaches. The company can also analyse energy metabolism, primary metabolism and lipid metabolism at the same time.

Finally, the company also focusses on fluxomics technology that is able to trace metabolic fluxes through biochemical routes. There, they provide information on labelling patterns (metabolite movement) and distribution using stable isotope labelling.

The company is looking to sign a research cooperation agreement or service agreement with any kind of business, research organisation or university active in the field pharmaceutical, biotechnology or food industry. They can imagine jointly solving research questions using their metabolomics platform or providing their own analytical services for a fee.
Advantages and Innovations:
Contrary to competitors with platforms analysing metabolites, this company is able to provide a set of information that goes far beyond normal offers. The company analyses all known and unknown metabolites in a sample using state-of-the-art mass spectrometry technologies. Unlike their competitors, the platform developed by the German company can additionally analyse energy metabolism, primary metabolism and lipid metabolism.
They offer customized solutions and adjust methods depending on the sample and the compound interest. Due to the large variation in physical properties of metabolites, the company employ different extraction and separation protocols.
Stage of Development:
Already on the market
IPs:
Secret Know-how

Partner sought

Type and Role of Partner Sought:
The company is looking for partners in in the pharmaceutical, biotechnology or food industry. Potential partners could range from small businesses to big multinationals or universities. The company offers focused small scale projects on a fee-for-service basis. Collaborative research project with a longer duration in time and complexity is done in the framework of a research cooperation contract.

Client

Type and Size of Client:
Industry SME 11-49
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
Dutch
English
French
German
Italian
Spanish

Dissemination

Restrict dissemination to specific countries:
Austria, Belgium, Canada, Denmark, Finland, France, Germany, Ireland, Israel, Italy, Japan, Korea, Republic Of, Netherlands, Norway, Spain, Sweden, Switzerland, United Kingdom, United States

Keywords

Technology Keywords:
06001001 Bioestadística, epidemiología
06003001 Bioinformática
06002001 Bioquímica / biofísica
06006 Biotecnología industrial
06001005 Diagnósticos, diagnosis