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Trazador para tomografía por emisión de positrones (PET) como detector del dolor

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TODE20160408003
Publicado:
28/04/2016
Caducidad:
28/04/2017
Resumen:
Dos universidades alemanas han desarrollado un trazador para tomografía por emisión de positrones (PET). Estos trazadores se emplean normalmente como herramienta terapéutica contra el cáncer. Los investigadores han demostrado que también pueden utilizarse en la detección, localización e intensidad del dolor. Las universidades buscan empresas o centros de investigación en el campo de métodos de diagnóstico y terapia del dolor con el fin de establecer acuerdos de licencia, cooperación en materia de investigación y evaluación.

Details

Tittle:
Converted positron emission tomography (PET)-tracer to be used as pain detector
Summary:
The cooperation of two German universities led to the development of a positron emission tomography (PET)-tracer. PET-tracers are normally used as therapeutic tool in cancer. The researchers proved that it can also be used for the detection of pain, localise its origin and intensity. The German universities offer potential partners the opportunity for licensing agreements as well as a further research co-operation and evaluation.
Description:
Pain is probably the most common symptom and sensation of a disease, and a big individual and socioeconomic challenge. Diagnostic tools are limited and do not result in clear mechanism-based insight into the etiology of the individual pain. One shortcoming is that nearly all diagnostic approaches rely on the communication with the patient about the location, the presentation and the intensity of pain. Therefore, a method to visualize the origin of pain and to make its intensity objectively measureable is an urgent medical need. It is also a prerequisite for patient stratification for the development and testing of novel therapeutic drugs.
PET-tracers are widely used as diagnostic and therapeutic tools in several types of cancer, besides other applications of visualization in various medical indications. However, there are so far only few reports, which utilize PET-tracer and PET-scan for the detection of pain.
Two German universities have provided proof that an established PET-tracer for use in cancer can be also utilized for the detection of pain as a second medical application. They found this tracer to be enriched at the peripheral site of pain (see image). The amount of tracer-enrichment strongly correlated with the measured change in pain sensitivity.
The German universities offer the opportunity for license agreements and further research to companies or research institutes in the field of diagnostic methods and pain therapy.
Advantages and Innovations:
One main advantage and innovation is the fact that an established PET-tracer finds a further useful application. Furthermore the following competitive advantages are to be mentioned:
- First method to visualize the localization and intensity of peripheral long lasting inflammatory as well as neuropathic pain
- The novel application of established PET-tracers gives access to a safe, reliable and objective measurement of pain
- This method suggests an application especially to define the location of pain and thus the area for potential therapeutic intervention
- The invention improves an objective patient stratification of neuropathic pain patients


Stage of Development:
Field tested/evaluated
IPs:
Patent(s) applied for but not yet granted
CommeR Statunts Regarding IPR Status:
Patent application in Europe

Partner sought

Type and Role of Partner Sought:
The German universities offer the opportunity for license agreements and further research to companies or research institutes in the field of diagnostic methods and pain therapy. Potential partners couldbe active in the field of healthcare, medical engineering or pharmaceutics.

Client

Type and Size of Client:
University
Already Engaged in Trans-National Cooperation:
No
Languages Spoken:
English
German

Keywords

Technology Keywords:
06001005 Diagnósticos, diagnosis
06001012 Investigaciones médicas
06001 Medicina, salud humana
06001013 Tecnología médica / ingeniería biomédica