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Universidad británica busca socios industriales para desarrollar conjuntamente una tecnología para un sistema de administración controlada de fármacos resistentes a abusos

Resumen

Tipo:
Oferta Tecnológica
Referencia:
TOUK20170302001
Publicado:
06/03/2017
Caducidad:
06/03/2018
Resumen:
Una universidad británica ha desarrollado un nuevo sistema de matriz polimérica que incluye materiales generalmente reconocidos como seguros (GRAS) biocompatibles y biodegradables mediante procedimientos científicos que se emplean para preparar sistemas de administración de fármacos con técnicas escalables de extrusión por fusión en caliente o micromoldeo. La universidad busca socios industriales con el fin de establecer acuerdos de cooperación técnica, comercialización con asistencia técnica y licencia, así como socios industriales para desarrollar el producto específico.

Details

Tittle:
UK university is seeking technical cooperations, commercial agreements with industrial partners for co-development of technology for an abuse resistant controlled drug delivery system or specific development using technology through a licencing agreement
Summary:
A UK university has invented a novel polymer matrix system comprising of biocompatible, biodegradable generally recognised as safe (GRAS) materials through scientific procedures that can be used to prepare drug delivery systems using readily scalable hot melt extrusion or micro moulding processing techniques. It is seeking industrial partners for technical cooperation, commercial agreements with technical assistance and/or licensing to an industrial partner for product specific development.
Description:
A UK university has invented a polymer matrix system comprising of biocompatible, biodegradable, GRAS status materials that can be used to prepare drug delivery systems using readily scalable hot melt extrusion or micro moulding processing technique.

Prescription opioid analgesics are an important component of modern pain management. Abuse and misuse of these products have created a serious and growing public health problem globally.

When the matrix is prepared with the drug substance, the resultant drug product will have the desired quality attributes required by the Food and Drug Administration (FDA) for Abuse Resistant Systems (tier 1) and has been shown to comply with FDA´s required product characteristics in the ability to crush and ease of extraction.

The prototype formulations also release the full drug loading over a 12 hour period and the rate of release can be modified by changing the blend of matrix components. The novel polymer matrix can also be formed into microneedles for controlled transdermal drug delivery using micro injection moulding processing techniques.

The abuse resistant formulations have been evaluated using different test conditions for in-vitro drug release studies.

The university is looking for industrial partners that have the capabilities to offer co-development of the technology through technical cooperation agreements or commercial agreements with technological assistance and also product specific development using the technology through a licencing agreement.
Advantages and Innovations:
An abuse resistant controlled release formulation designed for opioid drug delivery can be manufactured into convenient dosages using readily scalable processing techniques.

The release profile can be modified and optimised by changing the composition of the matrix.

The polymer matrix is acceptable in the pharmaceutical field, readily available and is made from inexpensive materials .

It can also be formed into microneedles for controlled transdermal drug delivery using readily scalable processing techniques.
Stage of Development:
Concept stage
IPs:
Secret Know-how

Partner sought

Type and Role of Partner Sought:
The university is seeking technical cooperation agreements, commercial agreements with technical assistance and licencing agreements with industrial partners for the co-development of the technology of the abuse resistance controlled drug delivery systems and also product specific development using the technology with the view to out-licencing the technology to the industrial partner .

Client

Type and Size of Client:
University
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English

Keywords

Technology Keywords:
06002007 Ensayos in vitro, experimentos
06001007 Medicina de urgencias
06001015 Productos farmacéuticos / medicamentos
06001006 Vacunas humanas