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Compañía farmacéutica de Reino Unido busca nuevas moléculas en fase temprana en el campo de inmuno-oncología

Resumen

Tipo:
Demanda Tecnológica
Referencia:
TRUK20161011001
Publicado:
02/11/2016
Caducidad:
02/11/2017
Resumen:
Una compañía farmacéutica de Reino Unido busca nuevas moléculas pequeñas con actividad inmuno-oncológica para cánceres difíciles de tratar. La empresa continuará con el desarrollo de las moléculas para mejorar sus perfiles de eficacia y seguridad, con vistas a licenciar las moléculas mejoradas a grandes compañías farmacéuticas y lanzar el producto al mercado. La empresa busca universidades, centros de investigación y pymes con el fin de establecer acuerdos de licencia o cooperación técnica.

Details

Tittle:
UK-based pharmaceutical SME seeks novel early stage molecules in the immuno-oncology space
Summary:
A UK-based pharmaceutical SME is looking for novel small molecules with immune-oncology activity especially in regard to difficult to treat cancers. The SME will further develop these novel compounds to improve their efficacy and safety profiles with a view to licensing the improved molecules to larger pharmaceutical companies to take onto the market. The SME seeks to partner with universities, research Institutes and SMEs in the form of a licensing agreement or technical cooperation agreement.
Description:
As cancer is expected to affect more than one in three people during their lifetime oncology is still a major field of medical research with a need for new treatments and new approaches. One such approach is the field of immune-oncology where the patient´s own immune system is stimulated so that cancer cells are recognised and destroyed by it. This type of treatment has the potential to provide effective, long-lasting therapy with fewer side effects.

A UK-based drug discovery and development company with subsidiary companies specialising in oncology, immunology and anti-infectives, is looking to partner with Universities, Research Institutions and other SMEs who may have novel small molecules with immune-oncological activity particularly against difficult to treat cancers. The SME is looking for very early stage small molecules that it can further develop the compounds by improving activity, drug-like properties and safety profiles. The company has expertise in medicinal chemistry, computational chemistry, pharmacology, drug metabolism and pharmacokinetics, analytical and business development; and are able to add significant value to a compound /program with the capability of taking the asset through preclinical development as well as Phase 1 clinical trial stage with the aim of licensing on to a larger pharmaceutical company for further development and market registration.

It is envisaged that the partnership with the University, Research Institution or SME would be in the form of a licensing agreement, although technical cooperation agreements will also be considered where appropriate.
Technical Specification or Expertise Sought:
The UK-based SME is looking for novel small molecules with activity in the immune-oncology space. They are especially looking for molecules at a very early stage of development. As well as access to the molecules and their chemical structure data the SME would also require information on the molecules´ target and the data generated to date on activity and safety profiles.

The SME is looking for novel small molecule compounds against a validated target. They are especially interested in novel targets but will require additional chemistry data in order to pursue these compounds. The molecules must have immune-oncology activity. The SME will not consider molecules with general chemotherapy mode of action nor compounds that are not novel.

Partner sought

Type and Role of Partner Sought:
The UK-based SME is looking to partner with Universities, Research Institutions and other SMEs that have identified novel small molecules with immune-oncology activity.

The UK-based SME will develop these early-stage molecules through an optimisation process improving their activity and safety profiles. The SME will take these molecules up to Phase 1 clinical trials with the aim of then licensing them on to larger pharmaceutical companies for later stage clinical trials.

It is anticipated that these partnerships will take the form of a licensing agreement whereby the SME will in-license the novel small molecules from the partner. Alternatively, a technical cooperation agreement will also be considered where appropriate.

Client

Type and Size of Client:
Industry SME 50-249
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English