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Compuestos cabeza de serie de molécula pequeña para numerosas indicaciones

Resumen

Tipo:
Demanda Tecnológica
Referencia:
TRUK20140918001
Publicado:
20/09/2016
Caducidad:
25/09/2016
Resumen:
Una organización de investigación por contrato tiene amplios conocimientos en química sintética y medicinal y ha creado una buena cartera de clientes en la industria farmacéutica. En los tres últimos años, la organización ha identificado cinco candidatos robustos para ensayos clínicos de sus clientes y busca nuevos compuestos cabeza de serie para desarrollar un candidato clínico robusto con unas propiedades determinadas. Los compuestos tienen pocos límites en cuanto a las indicaciones. La organización busca grupos de investigación y empresas en el campo de descubrimiento de fármacos con el fin de establecer acuerdos de joint venture o cooperación técnica.

Details

Tittle:
Small molecule hit and lead compounds for most indications
Summary:
An international chemistry contract research organisation has built an extensive skillset in synthetic and medicinal chemistry. They are looking for new hit and lead compounds that they could advance into a robust clinical candidate, with desired properties agreed upon in advance. They would share in the eventual commercial return but not the IP. There is little limit in terms of indication areas. Drug discovery businesses -Y- research groups are sought for joint ventures or technical cooperation.
Description:
An international chemistry contract research organisation has built an extensive skillset in synthetic and medicinal chemistry. At the same time, they have built a good customer base in the Pharma industry. The company has identified 5 robust candidates for clinical trials for their clients over the past 3 years.
They are interested in early stage small compounds that would benefit from optimisation or synthesis as a chemical or medicinal chemistry project. The idea is to explore dual contribution/dual return type projects. The parties will agree on a goal in terms of the desired potency etc that would be attractive for the Pharma industry. The chemistry company would contribute significantly towards the development of a robust compound with the agreed attributes and later share any commercial returns. At the same time they will not make any claims on the IP generated.
The company has worked in practically all indication areas so that is not a limitation. They would also consider a grant-funded project. Mostly, joint ventures and technical cooperation are sought around early stage small compounds. First, desired technical and commercial goals will be set followed by a detailed description of the involvement of either party.
Technical Specification or Expertise Sought:
What is sought is promising hit and lead compounds that are currently sub-optimal, with regards to their selectivity or specificity, or availability.

Partner sought

Type and Role of Partner Sought:
Type of partner sought: industry and academia;
- Type of activity of the partner: drug discovery and optimisation;
- Task to be performed by the partner sought: to provide non-confidential information on high priority projects and the type of collaboration envisaged. Mostly, joint ventures and technical cooperation are sought around early stage small compounds. First, desired technical and commercial goals will be set followed by a detailed description of the involvement of either party.

Client

Type and Size of Client:
Industry SME 50-249
Already Engaged in Trans-National Cooperation:
Si
Languages Spoken:
English