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Desarrollo de sistemas de prueba combinados para diagnóstico del infarto de miocardio

Resumen

Tipo:
Demanda Tecnológica
Referencia:
TRRU20140616001
Publicado:
24/06/2015
Caducidad:
30/12/2015
Resumen:
Una pyme rusa ha desarrollado una tecnología para el diagnóstico precoz del infarto de miocardio. Esta tecnología se basa en la identificación de proteínas de unión de ácidos grasos (FABP) como cardiomarcador y en una tecnología de ciclo completo para fabricar tiras de prueba. La empresa está interesada en desarrollar un método combinado para el diagnóstico de infarto de miocardio utilizando dos cardiomarcadores (FABP y troponina) y busca socios en los sectores de biotecnología, medicina, bioquímica y desarrollo de diagnósticos con el fin de establecer acuerdos de cooperación técnica e investigación.

Details

Tittle:
Development of combined test-systems for diagnostics of myocardial infarction
Summary:
A Russian SME from Kaluga region developed a technology for early diagnostics of myocardial infarction, based on the identification of a cardiomarker fatty-acid-binding protein (FABP) and a full-cycle technology for test-strips manufacture. The company wants to develop a combined method for myocardial infarction diagnostics using two cardiomarkers: FABP and troponin, and seeks partners for research and technical cooperation.
Description:
Laboratory diagnostics is playing an increasing role in the modern medicine as a main tool for making diagnosis and monitoring the progress of therapy. One of thriving and demanded methods of laboratory diagnostics is the immunochromatographic analisys - the method for identification of certain concentration of substances in biological liquids (urine, blood, saliva, etc.). This analisys is made with use of indicator test-stripes, which makes the testing fast and comfortable.

A small enterprise, in a partnership with a leading Russian research centre, developed an immunochromatographic technology for identification of a fatty-acid-binding protein (FABP) and a full-cycle technology for manufacturing test-strips for early diagnostics of myocardial infarction. The fatty-acid-binding protein allows seeing the changes taking part in the human body under a myocardial infarction during the first 5 hours. For a later diagnostics, the troponin cardiomarker is used. The concentration of this marker reaches the diagnostic threshold after 6 hours from the start of pain syndrome, archives the maximum after 18 hours and comes back to the initial level after 5-10 days.
The company looks for further improvement of the diagnostic technology and the development of a combined test-systems to allow diagnosing the myocardial infarction by two cardiomarkers: FABP and troponin; this would expand the working interval of myocardial infarction diagnostics from 1 to 72 hours from the appearance of pain syndrome.
The authors look for partners for scientific and technical cooperation, aimed at the development of a complex method for diagnostics of myocardial infarction by two cardiomarkers and further setting up a production of combined test-systems and antibodies used for manufacturing the test-systems.
Technical Specification or Expertise Sought:
The partner should have competences in biotechnology, medicine, biochemistry, development of diagnostic aids, including immunochromatographic tests. Availability of production facilities (or partners) would be a favour.

Partner sought

Type and Role of Partner Sought:
Industry, R&D institution, university in the area of medicine, biotechnology, health care, biochemistry, development of diagnostic aids, including immunochromatographic tests.

Tasks to be performed: Joint research aimed at the development of the technology and further setting up a production of combined test-systems for express diagnostics of myocardial infarction on the basis of the partner's research and production capacities.

Client

Type and Size of Client:
Industry SME <= 10
Already Engaged in Trans-National Cooperation:
No
Languages Spoken:
English