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Recuperación inmune de resfriado/gripe y reducción de la duración de los síntomas

Resumen

Tipo:
Demanda Tecnológica
Referencia:
13 GB 403U 3SOJ
Publicado:
11/02/2015
Caducidad:
30/08/2015
Resumen:
Una multinacional del sector sanitario busca tecnologías y enfoques para fortalecer el sistema inmunológico humano y acelerar el proceso de recuperación de enfermedades, como el resfriado y la gripe. Se buscan investigadores o empresas con tecnologías que reduzcan la duración de los síntomas causados por una enfermedad y disminuir la probabilidad de una futura infección o recaída. Como tecnologías potenciales se incluyen métodos físicos, biológicos o naturales e ingredientes que eliminen la infección vírica del cuerpo, reduciendo la carga del sistema inmunológico y contribuyendo a su rápida recuperación. La empresa está interesada en establecer acuerdos de cooperación técnica y licencia, así como en continuar con el desarrollo.

Details

Tittle:
Immune Recovery from Cold/Flu & Reduction in Symptom Duration
Summary:
An international healthcare group is seeking technologies and approaches that help boost the human immune system and assist in faster recovery from illness such as Cold & Flu. They are seeking researchers or companies with technologies that shorten the duration of symptoms caused by an illness and thus reducing chances of a subsequent infection or relapse. They are seeking technical cooperation, joint further development and licensing opportunities.
Description:
Cold and Flu symptoms are predominantly caused by Viral infections. Products which have an antiviral effect and/or assist in shortening the duration of associated symptoms (and speeding up immune recovery) are desirable propositions for many consumers.
- In addition to this, while cough & cold symptoms may only last several days, it can take between 10 to 14 days for the immune system to fully recover - during this time you're more susceptible to getting another infection. When in frequent and close contact with lots of other people (i.e. in an open office, or urban environment) this can manifest itself in an individual getting a string or series of infections - sometimes people will speak about this as getting "run-down".

Potential technologies would include chemical, physical, biological or natural/herbal methods or ingredients that help in removal/destruction of the viral infection from the body, reducing the "load" on the immune system and helping it recover quicker. Alternative approaches could be those that "up-regulate" the bodies innate immune system or may include Probiotic species which assist in antiviral and/or immune defense.
Technical Specification or Expertise Sought:
- Technologies to be taken only after onset of illness
- Shorten duration of Cold/Flu symptoms
- Decrease timeframe for immune system to return to full strength
- Solutions must demonstrate at least limited evidence of efficacy, supported by technical and ideally clinical data and have licensed medicine/CE marked medical device status where applicable
- Any Format acceptable
- Don't need to take everyday (i.e. even when your well) to provide protection - only take a "course" when your ill to get you back to full strength.
- Suitable for self administration - OTC
- Should be readily available in large quantities or proven suitable for large scale manufacture

For device-based approaches, it is desirable to have a consumable element (however this is not essential in the case of novel technologies).

Out of Scope:
- Supplements requiring "well" people to take them every day
- Early stage/ fundamental research
- Solutions without any supporting data

Other Details:

Technology leads should ultimately meet the following requirements for incorporation into a consumer product:
1) Compatible with typical pharmaceutical product and packaging e.g. HDPE, PET, and final formulation expected to be stable under global ambient temperature and humidity conditions for a period of 2 years
2) Not require storage or handling under special or inert conditions, e.g. under nitrogen or under oil.
3) Soluble or readily dispersed in the formulations and not negatively affect or interfere with the properties of other components in the formulation.
4) Able to be able to be incorporated into current products using simple batch mixing at room temperature and atmospheric pressure with minimal heating/cooling and no or minimal changes required to current clean down processes.
5) Cost appropriate for consumer products (when incorporated at the required level). As examples, this means maximum £20/kg (GBP) for an ingredient incorporated at 1-5%, and maximum £250/kg (GBP) for an ingredient incorporated at <0.1%
6) Must be listed on the following world-wide regulatory inventories:
· EINECS (http://ptcl.chem.ox.ac.uk/MSDS/glossary/EINECS.html),
· TSCA (http://www.epa.gov/opptintr/newchems/invntory.htm) & EPA Inerts list
· ELINCS (http://ptcl.chem.ox.ac.uk/MSDS/glossary/ELINCS.html),
· DSL (http://www.ccohs.ca/products/databases/dsl.html)
· AICS (http://www.nicnas.gov.au/obligations/aics/) - where possible.
· According to the Dangerous Preparations Direc

Partner sought

Type and Role of Partner Sought:
- Type of partner sought: Industry or researcher
- Specific area of activity of the partner: Medical products, pharmaceutical, medical devices, therapeutic
- Task to be performed by the partner sought: Provision of novel technology for joint further development or licensing agreement

Client

Type and Size of Client:
Industry >500
Already Engaged in Trans-National Cooperation:
No