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EURONANOMED II: Búsqueda de pymes e institutos de investigación/universidades para desarrollar un proyecto sobre biomateriales magnéticos para reparación y formación de imágenes de tejido cerebral


Búsqueda de socios
Un instituto de investigación español está preparando una propuesta para la convocatoria Euronanomed II (proyectos europeos de investigación y desarrollo tecnológico innovadores en nanomedicina). El objetivo es reparar y formar imágenes de tejido cerebral mediante biomateriales magnéticos. Se buscan pymes, institutos de investigación o universidades en Bélgica, Grecia, Italia, Israel y Francia para completar el consorcio. La fecha límite de la convocatoria es el 11 de febrero de 2016 y el plazo para presentar expresiones de interés finaliza el 15 de enero.


EURONANOMED II: SMEs and research institutes / universities sought for a "magnetic biomaterials for brain tissue repair and imaging" project
A Spanish research institute is preparing an application for Euronanomed II call (European Innovative Research -Y- Technological Development Projects in Nanomedicine). The purpose of the project is to repair and image brain tissue through magnetic biomaterials. SMEs, other research institutes or universities from Belgium, Greece, Italy, Israel and France are being sought to complete the consortium.
The project will address tissue repair guided by angiogenesis in the context of an ischemic event. The research institute will take advantage of the potential of nanotechnology to increase the accumulation of growth factors (pro- and anti-angiogenic) in the damaged areas. Moreover, in contrast to drug delivering systems or imaging agents alone, their theranostic materials will provide both imaging and treatment. Regenerative medicine has proposed therapeutic strategies based on the potentiation of angiogenesis that takes place during tissue repair and is linked to different remodeling processes.
Their approach will provide an advanced therapy that could be translated to a clinical stage as non-invasive, safe and available to most patients. In addition, such approach permits its implementation to the patient in several doses for an extended period of time. Biomaterials will be fully characterized including among others aspects cytotoxicity and therapeutic properties both in vitro and in vivo; advanced imaging techniques will be used to monitor and guide the delivery of the biomaterials and to assess the therapeutic effect in vivo over time.
Besides, they will devote research activities to study the encapsulation in biocompatible and biodegradable nanocapsules of cell secretomes, delivering them into the target brain area and imaging its implantation.

The proposer of this profile and coordinator of the proposal is a research group working on tissue repair and cell therapies in neurological diseases in a leading research institute of its country devoted to biomedical and translational research.

The group is focused in stroke research, a leading cause of death and disability worldwide without effective treatments for the 5 million people that survive a stroke every year but remain permanently disabled. In the last 8 years one of their research lines has been neurorepair based on cell therapies and focusing on angiogenesis mechanisms as repair mechanisms. They can prove strong background on this field which is the focus of the proposed project and within the scope of the Euronanomed II Call.

Several academic partners are already involved within the project. Strong collaboration with another research group in the materials science field (also participating in the consortium) that has obtained results in the biomaterials/repair field in terms of 3 publications (D1), one doctoral thesis and one patent in the last 5 years. Moreover, they have experience in both national and international projects and consortiums.
Therefore, mainly SMEs are being sought to fulfill the consortium.

Call: EURONANOMED II: "European Innovative Research -Y- Technological Development Projects in Nanomedicine"
Call deadline: 11/02/2016
Deadline for EoIs: 15/01/2016

Partner sought

Partner Sought:
2 types of partners are being sought for this project: 1) SME 1: Cells and growth factors up scaled fabrication according to GMP regulations 2) SME 2: Nanocapsules (PLGA) upscale fabrication according to Good Manufacture Practice (GMP) regulations, potentially also magnetic nanoparticles (SPIONs). A third partner could be also considered: 3) Research group (institute or university): To perform longitudinal in vivo imaging studies to guide and assess the delivery of the biomaterials and characterize the therapeutic effect in experimental models of ischemia using perfusion and angiographic magnetic resonance imaging (MRI), functional imaging technique and/or others.
Type of Partnership Considered:


Type and Size of Client:
R-Y-D Institution
Already Engaged in Trans-National Cooperation:


Restrict dissemination to specific countries:


Anticipated Project Budget:
700.000 -Y-euro;
Coordinator Required:
Deadline for Call:
Project Duration:
Project title and Acronym:
Magnetic Biomaterials for Brain Tissue Repair and Imaging